58例多药耐药革兰阴性菌肺炎患者抗感染治疗的疗效评价  

Clinical Efficacy of Anti-infection Medication in 58 Cases of Gramnegative Bacteria Pneumonia Patients with Multi-resistants

作　　者：何光华[1] 

机构地区：[1]赣南医学院第一附属医院,江西赣州341000

出　　处：《抗感染药学》2016年第5期1092-1094,共3页Anti-infection Pharmacy

摘　　要：目的:评价多药耐药革兰阴性菌肺炎患者抗感染治疗的临床疗效。方法:选取2014年6月—2015年9月就诊的多药耐药革兰阴性菌肺炎患者58例,将其随机分为对照组和观察组(每组30例);对照组患者给予常规抗感染治疗,观察组患者在对照组治疗的基础上给予利福平、多黏菌素B和亚胺培南治疗,比较两组患者治疗后的临床疗效。结果:观察组患者治疗后的总有效率为96.55%明显高于对照组为82.76%(P<0.05)。结论:采用多种抗菌药物联用治疗多药耐药革兰阴性菌肺炎患者的临床疗效确切,优于常规抗感染治疗。Objective： To evaluate the clinical efficacy of routine anti-infection combined with multiple antibiotics in multi-resistant Gram-negative bacteria pneumonia. Methods： The selected 58 cases of patients with multi-resistant Gram-negative bacteria pneumonia treated during June 2014 to September 2015 were randomly divided into control group and observation group （29 cases in each group）. The control group patients were given routine anti-infection treat- ment,while the observation group patients were given routine anti-infection treatment combined with multiple antibiotics （rifampicin, polymyxin B and imipenem） treatment. The total effective rates of the two groups patients after treatment were compared. Results： The total effective rate of treatment group was 96.55%, significantly higher than control group＇s 82.76%. The difference was statistically significant（P〈 0.05）. ConcLusion： The clinical efficacy of routine anti- infection combined with multiple antibiotics is higher in the treatment of multi-resistant Gram-negative bacteria pneu- monia than that of routine anti-infection treatment.

关 键 词：多药耐药革兰阴性菌肺炎 抗感染治疗 评价 

分 类 号：R969.4[医药卫生—药理学]