厦门市2012—2015年HIV感染者/AIDS病例首次CD4^+T淋巴细胞分析  

Analysis of the first CD4^+ T count test of newly detected HIV/AIDS in Xiamen from 2012 to 2015

作　　者：欧阳雪[1] 郑惠能[1] 马桂林[1] 陈娟娟[1] 

机构地区：[1]厦门市疾病预防控制中心传染病防制科,福建361000

出　　处：《社区医学杂志》2016年第21期20-23,共4页Journal Of Community Medicine

摘　　要：目的了解厦门市HIV感染者/AIDS病例首次CD4+T淋巴细胞水平及其影响因素。方法收集2012—2015年厦门市HIV感染者/AIDS病例基本资料及其首次CD4+T淋巴细胞计数资料。计量资料比较采用方差分析,多因素分析采用Logistic回归分析,P<0.05为差异有统计学意义。结果影响首次CD4+T淋巴细胞计数的因素有:年龄、婚姻状况、感染途径、样本来源、首次检测时间间隔。年龄越大,首次CD4+T淋巴细胞计数越低,差异有统计学意义(P<0.05);无配偶病例的首次CD4+T淋巴细胞计数显著高于有配偶,差异有统计学意义(P<0.05);不同感染途径对首次CD4+T淋巴细胞计数的影响差异有统计学意义(P<0.05);不同样本来源病例的首次CD4+T淋巴细胞计数比较,差异有统计学意义(P<0.05);不同首次检测时间间隔病例的首次CD4+T淋巴细胞计数比较,差异有统计学意义(P<0.05)。术前筛查、性病门诊是影响首次CD4+T淋巴细胞计数的主要因素(OR=0.31,95%CI为0.19~0.51;OR=0.54,95%CI为0.30~0.95)。结论厦门市感染者首次CD4+T淋巴细胞计数较低,应加大检测力度、扩大检测覆盖面,使感染者在感染早期就得以检测和确诊。Objective To understand count of the first CD4＋ T count test of newly detected HIV/AIDS in Xiamen and its influence factor. Methods The basic data and CD4 count of HIV/AIDS from 2012—2015 were collected and analyzed. Measurement data was processed by variance analysis, factors analysis was used by Logistic regression analysis P〈0.05 was considered statistically significant.Results The influence factors of first CD4＋ T were age, marriage, infection, sample source and time interval of firsttest. The count interval of first CD4＋ T were obvious lower with age（P〈0.05）. The count of married patients are higher than those unmarried（P〈0.05）. The count of first CD4＋ T in different route of infection was significant difference（P〈0.05）. The count of first CD4＋ T in different sample source was significant difference（P〈0.05）.The count of first CD4＋T in different time interval of first test was significant difference（P〈0.05）. Preoperative screening and STD clinic were the main influence factors of the first CD4＋ T count（OR=0.31,95%CI 0.19-0.51;OR=0.54,95%CI 0.30-0.95）. Conclusion The count of first CD4＋ T was low of patients in Xiamen. We should increase the intensity of detection, expand the detection coverage to find patient earlier.

关 键 词：HIV感染者 AIDS病例 CD4+T淋巴细胞计数 

分 类 号：R512.91[医药卫生—内科学]