儿童神经母细胞瘤伴骨转移的MSCT诊断  

MSCT findings of children metastatic neuroblastoma in bone

作　　者：周俊霖[1] 苗静[2] 黄素华[1] 丁山[1] 朱才娣[1] 徐红艳[3] 罗佳鑫 

机构地区：[1]江西省儿童医院放射科,江西南昌330006 [2]江西省儿童医院儿内科,江西南昌330006 [3]江西省儿童医院病理科,江西南昌330006

出　　处：《实用放射学杂志》2016年第11期1766-1768,1772,共4页Journal of Practical Radiology

摘　　要：目的探讨儿童神经母细胞瘤（NB）伴全身骨转移的临床特征及MSCT诊断。方法回顾性分析10例NB伴骨转移患儿的临床及MSCT资料，分析其影像学特征。10例均行腹部CT平扫及增强检查，其中胸部和头颅CT平扫及增强检查分别为3例和4例。结果10例NB患儿均伴有骨转移，其中3例伴有肝转移，另3例伴有远处淋巴结转移。4例为颅面骨转移，4例为骨盆转移，2例为脊柱转移，均表现为溶骨性骨质破坏，其周软组织肿块可见钙化及垂直状骨针。增强后软组织肿块及邻近脑膜有不均匀轻度强化。结论NB骨转移的临床及MSCT均有一定特征性，MSCT对本病的诊断有重要价值。Objective To explore the MSCT features of children metastatic neurobiastoma {NB} in bone. Methods The imaging findings in 10 patients with children metastatic NB in bone were analyzed retrospectively. Ten patients underwent plain and contrast- enhanced CT scan of abdomen. Additionally, 3 patients underwent plain and contrast-enhanced CT scan of chest, 4 patients under- went plain and contrast-enhanced CT scan of head. Results Among the 10 patients, bone metastasis involved skull （4 patients）, pel- vis（4 patients）, spine（2 patients） ,besides liver metastasis （3 patients） and distant lymph node metastasis （3 patients）. The 10 cases were all characterized by the bone destruction of osteolysis, calcification and spiculated periosteal reaction in soft tissue masses near- by. Slight heterogeneous enhancements in the soft tissue mass and adjacent meninge were observed. Conclusion The MSCT find- ings of children metastatic NB in bone has some characteristics which are helpful for diagnosis.

关 键 词：神经母细胞瘤 骨骼 转移 计算机体层成像 

分 类 号：R814.42[医药卫生—影像医学与核医学] R730.264[医药卫生—放射医学]