应用KDQOL—SF^TM1.3量表评价多中心维持性血液透析患者的生活质量  

Application of KDQOL-SFTM 1.3 version in evaluating quality of life of maintenance hemodialysis patients in multiple centers

作　　者：王丽雅[1] 王德光[2] 张秀军[1] 陈雷 史光彩 许家岭[5] 朱建军[5] 肖蓓[6] 刘莉[7] 任伟[8] 周长顺[9] 

机构地区：[1]安徽医科大学公共卫生学院流行病学与卫生统计学系,合肥230032 [2]安徽医科大学第二附属医院肾内科,合肥230601 [3]合肥市滨湖医院肾内科,合肥230061 [4]合肥市第五人民医院肾内科,合肥230061 [5]解放军第105医院肾内科,合肥230031 [6]合肥市第一人民医院肾内科,合肥230061 [7]合肥市第二人民医院肾内科,230011 [8]安徽省立医院肾内科,合肥230001 [9]安徽医科大学第一临床学院"5+3"一体化临床医学专业,合肥230032

出　　处：《中华肾脏病杂志》2016年第11期839-846,共8页Chinese Journal of Nephrology

摘　　要：目的了解维持性血液透析（maintenance hemodialysis，MHD）患者的生活质量及其影响因素，为提高患者生活质量提供理论依据。方法采用横断面研究，收集患者一般临床资料，并应用KDQOL—SF自填问卷量表对合肥市8所医院血液净化中心MHD患者的生活质量进行调查，描述患者健康相关生活质量并分析影响其生活质量的因素。结果合肥市MHD患者的生活质量水平较早先同类研究结果好，总体来讲，男性、高学历、家庭人均年收入高与患者生活质量呈正相关（P〈0．05），量表评分相对较高，原发病为糖尿病肾损害或药物性肾损害的患者在心理健康（mental component summaYy，MCS）、生理健康（physical component summary，PCS）、SF-总分及肾脏和透析相关生存质量（kidney disease-targeted areas，KDTA）总分均较低，Chadson合并症指数（CCI）与MCS、PCS、SF．总分呈负相关（P〈0．05），患者职业、医疗保险情况对患者MCS、KDTA总分具有影响（P〈0．05）。结论MHD患者的生活质量受多方面因素的影响，其中CCI、文化程度是MHD患者生活质量的独立影响因素，此外，患者性别、家庭人均年收入、原发病、职业、医疗保险情况对生活质量也有一定影响。Objective To understand the quality of life （QOL） and its influencing factors in maintenance hemodialysis patients （hemodialysis maintenance, MHD）, and to provide theoretical basis for improving QOL of patients. Methods A crosssectional study was conducted in the blood purification centre in 8 hospitals of Hefei, and patients clinical data were collected. KDQOL-SF selfadministered questionnaire was applied to assess the health related quality of life （HRQL） of patients and to analyze the factors influencing the QOL. Results The QOL of MHD patients in Hefei City was better compared with previous similar research results. Generally speaking, gender （male）, education degree and household income were positive correlated with QOL scores （P 〈 0.05）, and the scores of primary disease of patients with diabetic nephropathy or drugs were lower （P 〈 0.05） in physiological component summary （PCS）, mental component summary （MCS）, SF- 36 and KDTA. Charlson comorbidity index （CCI） was negatively correlated with the MCS scores, PCS scores and SF scores （P 〈 0.05）, and patients＇ occupational and medical insurance had impacts on MCS and KDTA score （P 〈 0.05）. Conclusions The QOL of MHD patients are affected by many factors, and the CCI and cultural level are possible independent influencing factors. In addition, gender, household income per capita, primary disease, occupation, medical insurance also have certain influence.

关 键 词：肾透析 生活质量 KDQOL-SF量表 Charlson合并症指数 

分 类 号：R692.5[医药卫生—泌尿科学]