自体血清皮肤试验在慢性荨麻疹中的临床应用价值分析  

Analysis of the clinical value of autologous serum skin test in chronic urticaria

作　　者：杨素莲[1] 谢淑霞[1] 尹颂超[1] 区凤仙[1] 张云青[1] 赖维[1] 

机构地区：[1]中山大学附属第三医院皮肤性病科,广东广州510630

出　　处：《中国卫生检验杂志》2016年第21期3158-3160,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨自体血清皮肤试验(ASST)在慢性荨麻疹中的临床应用价值。方法收集慢性荨麻疹患者,进行自体血清皮肤试验,并分析试验结果阳性和阴性患者的临床特点。结果共收集79例慢性荨麻疹患者,其中43例出现ASST阳性反应,阳性率为54.43%;20名健康自愿者ASST全部阴性。ASST阳性患者的病程明显长于阴性患者,且风团数量多、面积大,瘙痒程度更明显,临床体征评分更高,差异均有统计学意义(P<0.05)。结论慢性荨麻疹患者中自体血清皮肤试验阳性患者的临床表现比阴性患者更严重,具有一定的临床应用价值。Objective To investigate the clinical value of autologous serum skin test（ ASST） in chronic urticaria（ CU）. Methods CU patients were included and given ASST,and the clinical features of patients with positive and negative results were analyzed. Results A total of 79 CU patients were collected,among which 43 patients showed positive response to ASST,and the positive rate was 54. 43%. 20 healthy volunteers were all ASST- negative compared to ASST- negative patients. ASST- positive patients exhibited longer clinical courses,showing more wheal number,larger wheal area,more serious itching degree,and higher scores on clinical manifestation,with the differences statistically significant（ P〈0. 05）. Conclusion CU patients have a higher ASST positive rate,and the clinical manifestations of ASST- positive patients are severer than those of ASST- negative patients. Therefore,ASST is clinically valuable for CU.

关 键 词：慢性荨麻疹 自体血清皮肤试验 自身抗体 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]