阴茎负压吸引联合小剂量他达拉非治疗糖尿病性勃起功能障碍的临床观察  

Tadalafil combined with vacuum erection devices therapy in the treatment of diabetic men with erectile dysfunction

作　　者：李韬[1] 谢子平[1] 谭艳[1] 谢胜[1] 

机构地区：[1]湖北医药学院附属人民医院男科,湖北十堰442000

出　　处：《中国性科学》2016年第11期8-10,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探讨阴茎负压吸引(VED)联合小剂量他达拉非口服治疗糖尿病性勃起功能障碍(EDDM)的有效性和安全性。方法:选取70例DED患者,随机将其分为治疗组和对照组各35例,对照组给予他达拉非片5mg口服,每晚1次,8周为1疗程。治疗组在对照组治疗的基础上加用真空阴茎负压吸引治疗8周;比较治疗前、治疗结束时的IIEF-5评分、性生活日志(Sexual Encounter Profile,SEP)中的SEP-Q2(successful penetration)、SEP-Q3(successful completion of intercourse)变化。结果:两组患者治疗后IIEF-5评分、插入成功率及性交成功率均较治疗前提高(P<0.05),试验组IIEF-5评分治疗前、治疗结束分别为(11.61±2.89)、(20.85±2.18),对照组IIEF-5评分治疗前、治疗结束时分别为(11.38±3.15)、(17.40±2.64),治疗后插入成功率(SEP-Q2)两组分别为62.9%、91.4%,性交成功率(SEP-Q3)两组分别为60%、91.4%,联合治疗组相比较效果更明显(P<0.05),两组均未出现严重不良反应。结论:真空负压吸引联合小剂量他达拉非口服治疗糖尿病性ED疗效显著,值得临床应用。Objectives： To assess the efficacy and safety of combination therapy of tadalafil and vacuum erection devices in the treatment（ VED） of type 2 diabetes mellitus men with erectile dysfunction（ EDDM）.Methods： 70 patients with EDDM were randomly divided into two groups. Group A（ n = 35） were treated with tadalafil（ 5mg/day） only,whereas group B（ n = 35） were treated with combination therapy,including tadalafil 10 mg and vacuum erection device. International Index of Erectile Function（ IIEF-5） and Sexual Encounter before and after the treatment were compared. Results： IIEF-5 scores,successful penetration and successful intercourse of two groups were all markedly increased（ P〈0. 05）. IIEF-5 scores of group B before and after treatment were（ 11. 61 ± 2. 89） and（ 20. 85 ± 2. 18）; IIEF-5 scores of group B were（ 11. 38 ± 3. 15） and（ 17. 40 ± 2. 64）. After treatment,the successful penetration rate of two groups were 91. 4% and 62. 9%,the successful intercourse of two groups were 91. 4% and 60%. The effect of group B was better than group A. Conclusion： Combined treatment of tadalafil and vacuum erection device therapy can significantly enhance erectile function,which is worth of being widely applied in clinic.

关 键 词：阴茎负压吸引 他达拉非 糖尿病 勃起功能障碍 

分 类 号：R698[医药卫生—泌尿科学]