痰热清注射液对老年AECOPD伴肺炎患者疗效及血清sTREM-1、IL-6水平的影响  

Effects of Tanreqing Injection on Clinical Efficacy and sTREM-1, IL-6 levels in Elder Patients with Pneumonia Combined with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

作　　者：李丽娟[1] 刘志刚[1] 安志红[1] 李晓东[1] 

机构地区：[1]唐山市丰润区中医医院,河北唐山064000

出　　处：《现代中药研究与实践》2016年第5期78-80,共3页Research and Practice on Chinese Medicines

摘　　要：目的研究痰热清注射液治疗老年慢性阻塞性肺疾病急性发作期(AECOPD)伴肺炎患者的疗效及对血清可溶性髓样细胞触发受体-1(s TREM-1)、白细胞介素-6(IL-6)水平的影响。方法选取唐山市丰润区中医医院收治的AECOPD伴肺炎患者104例,治疗组患者在对照组治疗基础上加用痰热清注射液,疗程14 d。比较两组疗效、肺功能、炎性因子及安全性。结果治疗组患者临床总有效率显著大于对照组;治疗组患者治疗后肺功能指标均大于对照组,且血清s TREM-1、IL-6水平明显低于对照组。结论痰热清注射液治疗老年AECOPD伴肺炎患者效果显著,可减轻患者炎性损伤。Objective To investigate the effects of Tanreqing injection on the clinical efficacy and serum levels of sTREM- 1, IL-6 in elder patients with pneumonia combined with AECOPD. Methods 104 patients were randomly divided into control and experimental group （received Tanreqing injection and conventional treatment）. The treatment duration was 14 days. The total effective rates, lung function, inflammatory cytokines level and drug safety were compared. Results The total effective rate of experimental group was significantly higher than control group. Compared with the control group, the values of lung function index significantly increased in experimental group, and the levels of sTREM-1 and IL-6 decreased dramatically. Conclusion Tanreqing injection for eider patients with pneumonia and AECOPD has a significant clinical effect, and can attenuate inflammatory injury.

关 键 词：痰热清注射液 慢性阻塞性肺疾病 肺炎 可溶性髓样细胞触发受体-1 

分 类 号：R285.6[医药卫生—中药学]