血清学指标在老年股骨粗隆骨折患者中的变化及临床意义  

作　　者：单浩[1] 夏守慧[1] 沈娟[1] 杨海燕[1] 

机构地区：[1]浙江湖州中国人民解放军第九八医院检验科,313000

出　　处：《浙江临床医学》2016年第12期2183-2184,共2页Zhejiang Clinical Medical Journal

摘　　要：目的探讨血清学相关指标在老年股骨粗隆间骨折（FIF）患者中的变化和临床意义。方法对2012年5月至2014年5月行接受内固定手术治疗的98例老年FIF患者的临床资料进行回顾性分析，并纳入观察组，选择同期体检的非骨折人员56例为对照组，比较分析血清碱性磷酸酶（ALP）、超敏C反应蛋白（hsCRP）、γ-谷氨酰转肽酶（GGT）、降钙素原（PCT）的变化情况。结果观察组血清ALP、hsCRP、GGT、PCT的表达水平显著高于对照纽（P〈0．05）；术后随访1年，观察组死亡19例，存活的79例患者中31例出现各种并发症；死亡患者和出现并发症患者的血清ALP、hsCRP、GGT、PCT的表达水平明显高于存活者和无并发症者（P〈0．05）。结论老年股骨粗隆间骨折患者的血清学指标较健康人明显增高，相关血清学指标的检查对于预测老年股骨粗隆间骨折的预后具有重要意义。Objective To investigate of serum index clinical significance in aged patients with intertrochantric fracture.Methods 98 aged patients with intertrochanteric fracture were included into the observation group, 56 elderly people without fracture examination were included into the control group, the serum ALP, hsCRP, GGT, PCT levels were compared, and those with different prognosis were compared. Results The serum ALP, hsCRP, GGT and PCT levels in observation group were significantly highe than the control group （ P〈0.05 ） ; after follow-up of one year, there were of 19 patients, 31 patients with complications in 79 patients survied, serum ALP, hsCRP, GGT and PCT levels in death group and complication group were significantly higher than the survival group and non-complication group, the differences were of statistically significant （ P〈0.05 ） . Conclusions In elderly patients with femoral intertrochanteric fracture of serological indexes significantly higher, more healthy for checking related serological index for predicting the prognosis of elderly femoral intertrochanteric fractures has important significance.

关 键 词：股骨粗隆骨折 老年患者 骨质疏松 氧化应激 

分 类 号：R683.420.5[医药卫生—骨科学]