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机构地区:[1]江西省鹰潭市中国人民解放军第184医院重症医学科,335000
出 处:《浙江临床医学》2016年第12期2284-2285,共2页Zhejiang Clinical Medical Journal
摘 要:目的分析重症肺炎合并急性呼吸窘迫征的临床特点及预后影响因素。方法随机选取2014年4月至2016年4月重症肺炎合并急性呼吸窘迫征患者80例,依据病死情况将患者分为病死组(n=55)和存活组(n=25)。采集两组患者的痰液标本,采用全自动细菌鉴定仪鉴定其病原体,然后对两组患者的临床特点及预后影响因素进行统计分析。结果80例患者中,病死55例,存活25例,病死率为68.8%。病死组患者的年龄显著高于存活组(P〈0.05),机械通气时间、住院时间均显著短于存活组差异有统计学意义(P〈0.05)。但两组患者性别差异不显著(P〉0.05),感染源构成比之间的差异不显著(P〉0.05),均主要为病毒、细菌,其次为真菌,最后为混合。病死组患者的氧合指数显著低于存活组(P〈0.05),但两组患者的体温、血钠、血钾、血沉、脉搏、呼吸、pH值、动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)、吸氧浓度(FiO2)、白细胞计数(WBC)、血小板、血红蛋白(Hb)、白蛋白(Alb)、血尿素氮(BUN)、血肌酐(Scr)、总胆红素(TBIL)、C反应蛋白(CRP)、血沉、降钙素原(PCT)之间的差异均无统计学意义(P〉0.05)。结论重症监护病房重症肺炎合并急性呼吸窘迫征患者具有较高的病死率,其预后影响因素包括年龄、机械通气时间、住院时间及氧合指数。Objective To analyze severe pneumonia clinical characteristics and prognostic factors in patients with acute respiratory distress syndrome. Methods from April 2014 to April 2016 were randomly selected for severe pneumonia complicated with acute respiratory distress syndrome in patients with 80 cases, according to the prognosis of these patients were divided into death group ( n=55 ) and survival group ( n=25 ) . The two groups were collected sputum. The use of automatic bacteria identification system tO identify the pathogens, then the clinical Characteristics and prognosis of patients in two groups were analyzed. Results of the 80 patients, 55 eases died, 25 cases survived, the age of 68.8%. disease death group the mortality of patients was significantly higher than the survival group ( P〈0.05 ) , mechanical ventilation time, hospitalization time were significantly shorter than the survival group ( P〈0.05 ) , but no significant gender differences in the two groups of patients ( P〉0.05 ) , the difference between a source of infection than not significant (P〉0.05) , mainly for viruses, bacteria, followed by fungi, The last is mixed; death group, oxygenation index was significantly lower than the survival group ( P〈0.05 ) , but the two groups of patients with body temperature, serum sodium, serum potassium, ESR, pulse, respiration, pH value, arterial oxygen pressure (PaO2) , carbon dioxide partial pressure (PaCO2) , oxygen concentration ( FiO2 ) , white blood cell ( WBC ) , platelet count, hemoglobin ( Hb ) , albumin ( Alb ) , blood urea nitrogen ( BUN ) , serum creatinine ( Scr ) , total bilirubin ( TBIL ) , C reactive protein ( CRP ) , erythrocyte sedimentation rate, procalcitonin ( PCT ) between the difference was not significant (P〉0.05 ) . Conclusion ICU severe pneumonia complicated with acute respiratory distress syndrome patients has a higher rate of mortality, the prognostic factors including age, mechanical ventilation
关 键 词:重症监护病房 重症肺炎合并急性呼吸窘迫征 临床特点 预后 影响因素
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