大孔吸附树脂对驼血多肽的吸附行为研究  

STUDY ON ADSORPTION BEHAVIOR OF POLYPEPTIDES FROM CAMEL BLOOD ON MACROPOROUS ADSORPTION RESIN

作　　者：刘毅[1,2] 刘永峰[1,2] 裴栋[1,2] 魏鉴腾[1,2] 邸多隆[1,2] 

机构地区：[1]中国科学院兰州化学物理研究所中国科学院西北特色植物资源化学重点实验室和甘肃天然药物重点实验室,兰州730000 [2]青岛市资源化学与新材料研究中心,青岛266100

出　　处：《离子交换与吸附》2016年第5期385-393,共9页Ion Exchange and Adsorption

基　　金：国家自然科学基金(21544013);内蒙古自治区科技计划项目;阿拉善盟科技计划项目;阿左旗科技计划项目;中科院"西部之光"项目;甘肃省自然科学基金项目(1501RJZA011);青岛市民生科技计划项目(14-2-3-51-NSH);国家高技术研究发展计划(863计划;SS2014AA022203)

摘　　要：利用Langmuir、Freundlich、Temkin-Pyzhev和Dubinin-Radushkevich等温线模型,以及准一级动力学、准二级动力学、粒子内扩散、Boyd和Elovich模型,对驼血多肽在大孔吸附树脂上的吸附行为进行了系统研究。吸附等温线研究表明,驼血多肽分子在大孔吸附树脂上的吸附等温线属于Brunauer吸附等温线分类中的类型II;该吸附过程属于多层吸附过程,且属于简单的物理吸附,但其吸附作用力相对较弱。吸附动力学研究表明,驼血多肽在AUKJ-1的吸附过程属于慢吸附类型,可以很好的地利用准二级动力学模型进行拟合,受到外部传质和粒子内扩散的共同控制,有明显的活化能变化。该研究结果可为使用大孔吸附树脂分离纯化驼血多肽的工艺研究提供理论指导和技术支持,为驼血产品的深度开发和综合利用提供科学依据。Adsorption behaviors of polypeptide from camel blood polypeptide on macroporous adsorption resin were systematically researched utilizing Langmuir, Freundlich, Temkin-Pyzhev and Dubinin-Radushkevich isotherm models, and kinetic models such as Pseudo-first-order, Pseudo-second-order, intralntra-particle diffusion, Boyd and Elovich models. The results from adsorption isotherms indicated that adsorption isotherms of camel blood polypeptide on macroporous adsorption resin were type II classified by Brunauer. It was multi-layer adsorption and the adsorption process was feasible. The adsorption forces were comparatively weak, belonging to physical adsorption process. The results from adsorption kinetics demonstrated that adsorption of camel blood polypeptide on macroporous adsorption resin was attributed to slow adsorption type, fitted better by Pseudo-second-order kinetic model, controlled by exterior mass transfer and Intra-particle diffusion together, and obvious change of activation energy happened. The results will provide theoretical direction and technical support for separation and purification of camel blood polypeptide utilizing macroporous adsorption resin, and scientific evidence for deep development and comprehensive utilization of camel blood products.

关 键 词：大孔吸附树脂 驼血多肽 吸附行为 吸附等温线 吸附动力学 

分 类 号：O647.3[理学—物理化学]