血红蛋白水平对急性ST段抬高型心肌梗死病人预后的影响  

Influence of hemoglobin level on prognosis in patients with acute ST elevation myocardial infarction

作　　者：刘惊今[1] LIU Jing-jin(Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150086, China)

机构地区：[1]哈尔滨医科大学第二附属医院心内科,黑龙江哈尔滨150086

出　　处：《心血管康复医学杂志》2016年第5期464-467,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：心肌缺血省部共建教育部重点实验室开放基金(KF201304);黑龙江省博士后基金(LBH-Z14218);中国博士后科学基金(2014M56137)~~

摘　　要：目的:分析血红蛋白(Hb)水平与急性ST段抬高型心肌梗死(STEMI)患者预后的关系。方法:入选2011年1月至2014年1月我院STEMI患者1941例,依据护理过程中第一次检测到的Hb水平,分为:非贫血组(Hb≥120g/L,1638例),轻度贫血组(90g/L≤Hb<120g/L,221例)和中度贫血组(60g/L≤Hb<90g/L,82例)。观察患者在住院期和随访期主要心血管不良事件(死亡、充血性心力衰竭、心肌梗死/再梗、卒中)发生率。结果:随着贫血程度的减轻,平均年龄逐渐下降(P<0.01);随访期间,随着贫血程度的减轻,死亡率(42.7%比24.4%比7.5%),充血性心衰发生率(20.7%比10.9%比5.3%),主要心血管不良事件发生率(50.0%比27.1%比8.4%)明显降低(P<0.05或<0.01)。结论:在STEMI患者中,贫血患者在随访期间内死亡率、主要心血管不良事件的发生率明显高于非贫血组,且随着贫血程度的加重,死亡率和主要心血管不良事件发生率明显升高。Objective：To analyze the relationship between hemoglobin（Hb）level and prognosis in patients with acute ST elevation myocardial infarction（STEMI）.Methods：A total of 1941 STEMI cases were selected in our hospital from Jan2011 to Jan 2014.According to first detected Hb level during nursing,patients were divided into non-anemia group（Hb≥120g/L,n=1638）,mild anemia group（（90g/L≤Hb120g/L,n=221）and moderate anemia group（60g/L≤Hb90g/L,n=82）.Incidence rate of major adverse cardiovascular events（MACE,including death,congestive heart failure,myocardial infarction/reinfarction and stroke）during hospitalization and follow-up period was observed in all groups.Results：Mean age gradually reduced along with anemia degree decreased,P〈0.01;during follow-up,along with anemia degree reduced,there were significant reductions in mortality（42.7% vs.24.4% vs.7.5%）,incidence rates of congestive heart disease（20.7% vs.10.9% vs.5.3%）,MACE（50.0% vs.27.1% vs.8.4%）,P〈0.05or0.01.Conclusion：In STEMI patients,mortality and incidence rate of MACE during follow-up in anemia patients are significantly higher than those of non-anemia group,and they significantly rise along with anemia degree aggravates.

关 键 词：血红蛋白类 心肌梗死 预后 

分 类 号：R542.220.9[医药卫生—心血管疾病]