基于聚己内酯/二氧化硅复合材料的骨科固定材料的研究  

Study of orthopedics fixation material based on poly(ε-caprolactone)/fumed silica composite

作　　者：张丽[1] 贾守玉 赵宗浩 张恒[1] 张巍[1] 董军[2] 陈红余[1] 董建[1] 

机构地区：[1]泰山医学院化工学院,山东泰安271016 [2]泰山医学院运动医学与康复学院,山东泰安271016

出　　处：《泰山医学院学报》2016年第9期998-1000,共3页Journal of Taishan Medical College

基　　金：国家级大学生创新训练项目(201410439011);泰山医学院科研课题(2010ZR024)

摘　　要：目的制备一种基于聚己内酯/二氧化硅(PCL/SiO_2)复合材料的骨科固定材料。方法以PCL为基质,过氧化苯甲酰(BPO)为交联剂,气相法二氧化硅为增强剂,采用化学交联法制备PCL/SiO_2复合材料,并对其力学性能和热性能进行表征。将PCL/SiO_2复合材料裁制成适宜规格的骨固定材料以初步考察其塑形效果和X射线通透性。结果 PCL/SiO_2复合材料的强度较PCL明显改善,复合材料中PCL的结晶熔融温度为56℃。目标材料60℃即可软化塑形,且其X射线通透性优于石膏绷带。结论目标材料是一种理想的骨科固定材料,有望在临床上替代石膏绷带和小夹板。Objective：To prepare a kind of orthopedics fixation material based on poly（ε-caprolactone）/ fumed silica （PCL/ SiO2 ）composite. Methods：PCL/ SiO2 composite was prepared by chemical crosslinking,using benzoyl peroxide （BPO）as initiator,fumed silica as reinforcing agent. The mechanical and thermal properties of the composites were stud-ied. Orthopedics fixation material was made of PCL/ SiO2 composite with suitable size for preliminary study of its shaping effect and X ray permeability. Results：Compared with PCL,the mechanical strength of PCL/ SiO2 composites was signifi-cantly improved. The crystalline melting temperature of PCL in the composite was 56 ℃ . The objective material was sof-tened and shaped at 60 ℃ and its X ray permeability was better than plaster bandage. Conclusion：The objective material is an ideal material for orthopedics fixation and it can be expected to replace plaster bandage and small splint in clinic.

关 键 词：聚己内酯 气相法二氧化硅 化学交联 骨科固定材料 

分 类 号：R318.08[医药卫生—生物医学工程] R68[医药卫生—基础医学]