复方芦荟涂膜剂的制备工艺及研究  

Preparation Technology of Compound Aloe Plastic and Its Research

作　　者：张晶 贾佳 布秀娟 

机构地区：[1]大庆医学高等专科学校,黑龙江大庆163312

出　　处：《中国卫生产业》2016年第23期158-160,共3页China Health Industry

摘　　要：目的优选复方芦荟涂膜剂的最佳制备工艺,并对其进行质量控制。方法采用正交试验法对聚氧乙烯的用量、甘油的用量及乙醇的用量3个因素进行研究,以涂膜剂的成膜时间和外观性状为指标优选涂膜剂的制备工艺,采用HPLC法对涂膜剂中芦荟苷进行含量测定。结果复方芦荟涂膜剂的最佳制备工艺为药材提取浓缩液10 m L,聚乙烯醇-124 5 g,甘油6 m L,95%乙醇20 m L,氮酮1 m L。结论该涂膜剂制备工艺设计合理,制备工艺简单。Objective To select the best preparation technology of compound aloe plastic and carry out the quality control of it. Methods The dosages of polyoxyethylene, glycerol and alcohol were researched by the orthogonal experiment method,the plastic preparation technology was preferably selected according to the plastic membrane time and appearance, and the content of aloin in plastic was measured by HPLC method. Results The best preparation technology of compound aloe plastic was that 10 ml concentrate,-124 5g polyving akohol, 6ml glycerol, 20 ml 95% alcohol and 1ml azone were extracted by medicinal materials. Conclusion The design of the plastic preparation technology is rational and the preparation technology is easy.

关 键 词：复方芦荟涂膜剂 正交试验 制备工艺 

分 类 号：R944[医药卫生—药剂学]