罗哌卡因联合右美托咪定星状神经节阻滞治疗颈心综合征的疗效  

Efficacy of stellate ganglion block with ropivacaine combined with dexmedetomidine in the treatment of cervical cardiac syndrome

作　　者：尹学军[1] 宁贤友[1] 毕经斌[1] 

机构地区：[1]安徽省合肥市第八人民医院麻醉科,238000

出　　处：《实用疼痛学杂志》2016年第4期280-283,共4页Pain Clinic Journal

摘　　要：目的探讨颈心综合征应用星状神经节阻滞治疗的临床疗效。方法选择我科疼痛门诊颈心综合征患者33例，采用随机数字表法分为联合用药阻滞组（n=18）和单纯用药阻滞组（n=15）。联合用药阻滞组采用罗哌卡因和右美托咪定进行星状神经节阻滞治疗，单纯用药阻滞组仅用罗哌卡因行星状神经节阻滞，每日阻滞1次，7次为1个疗程，共两个疗程。两个疗程后第1个周一观察比较两组患者临床症状、生活质量评分的变化及临床疗效。结果治疗后，两组患者症状评分、SF-36评分均低于治疗前；联合用药阻滞组症状评分、SF-36评分分别为（8．9±0．6，6．4±2．6）均低于单纯用药阻滞组（12．6±0．5，9．1±3．7）（／9〈0．05）；两组临床疗效比较，联合用药阻滞组的有效率8313％（15／18例）优于单纯用药阻滞组66．7％（10／15例）（P〈0．05）。结论罗哌卡因联合右美托咪定行星状神经节阻滞治疗颈心综合征有较好的临床效果．可显著改善患者临床症状。Objective To explore the clinical efficacy of stellate ganglion block （SGB） with ropivacaine combined with dexmedetomidine in the treatment of cervical cardiac syndrome. Methods Thirty-three patients with cervical cardiac syndrome were randomly divided into combined drug block group （n=18） and single drug block group （n=15）. The patients in combined drug block group were given SGB with ropivacaine and dexmedetomidine, the single drug block group with ropivacaine only, once per day, 7 times for one course of treatment, a total of two courses. The changes of the clinical symptom, quality of life score （ST-36） and the clinical efficacy were observed in the first Monday after 2 courses of treatment. Results Compared with pretreatment, the scores of clinical symptom and SF-36 were both lowered in the first Monday after 2 courses of treatment in the two groups. Compared with single drug block group （ 12.6 ± 0.5,9.1 ±3.7） ,they were even lower in combined drug block group （8.9 ± 0.6,6.4 ± 2.6） （P〈 0.05）. The effective rate was higher in combined drug block group 83.3% （15/18 cases） than that in single drug block group 66.6% （10/15 cases） （P〈 0.05）. Conclusion Stellate ganglion block with ropivacaine and dexmedetomidine is effective in the treatment of cervical cardiac syndrome,with clinical symptoms improved significantly.

关 键 词：颈心综合征 星状神经节 神经传导阻滞 右美托咪定 酰胺类 

分 类 号：R614[医药卫生—麻醉学]