甲氨喋呤联合明胶海绵栓塞子宫动脉治疗宫颈妊娠效果分析  

Analysis of the effect of methotrexate combined with gelatin sponge embolization of uterine arteries in the treatment of cervical pregnancy

作　　者：黄达敏 曾小燕 

机构地区：[1]兴山县人民医院,湖北宜昌443700

出　　处：《中国处方药》2016年第12期4-5,共2页Journal of China Prescription Drug

摘　　要：目的探讨甲氨喋呤联合明胶海绵栓塞子宫动脉治疗宫颈妊娠的效果。方法选取2014年3月～2015年2月收治入院行甲氨喋呤联合明胶海绵栓塞子宫动脉治疗的10例宫颈妊娠患者为研究对象，对其临床资料进行回顾性分析，比较治疗前后出血量、血β-HCG（人绒毛膜促性腺激素）水平、并发症发生情况以及月经恢复情况等。结果术后3d血β-HCG为（1439．34±674．8）mIU／mL，明显低于术前的（4797．8±2249．6）mIU／mL；术后3d出血量为（78．5±21．5）mL，明显小于术前的（2136．4±1344.3）mL，差异均具统计学意义（P〈0．05）。结论甲氨喋呤联合明胶海绵栓塞子宫动脉治疗宫颈妊娠具有较好效果，可降低患者血β-HCG水平，有效止血，减少并发症发生。Objective To explore the effect of methotrexate combined with gelfoam embelization of uterine arteries in the treatment of cervical pregnancy. Methods Ten patients with cervical pregnancy undergoing methotrexate combined with gelfoam embolizatian in the treatment of uterine artery in our hospital from March 2014 to February 2015 were collected as the research subjects, and their clinical data were retrospectively analyzed. The post operative blood loss, the levels of blood β -HCG （human chorionic gonadotropin） and the complications were compared before and after the treatment. Results The level of blood -HCG on the third day after the operation was （ 1 439.34±674.B） mIU/mL, significantly lower than that before the operation （4 797.8 ±2 249.6） mIU/mL. The postoperative blood loss on the third day after the operation （78.5± 21.5 ） mL was significantly Less than that before the operation （2 136.4± 1 344.3 ） mL （P 〈 0.05）. Conclusion Methotrexate combined with gelfoam embolization of uterine artery is effective in the treatment of cervical pregnancy, it can reduce the level of HCG, stop bleeding and reduce the complications.

关 键 词：甲氨喋呤 明胶海绵 栓塞子宫动脉治疗 宫颈妊娠 

分 类 号：R714.22[医药卫生—妇产科学]