近10年支气管哮喘慢性持续期中医发病特点的文献研究  

Literature research on TCM characteristics of chronic persistent bronchial asthma in recent decade

作　　者：孙慧媛[1,2] 孙瑞华[3] 袁超 张秀艳[5] 韩健[6] 李友林[3] 

机构地区：[1]中国中医科学院西苑医院,北京100091 [2]中国中医科学院博士后科研流动站,北京100700 [3]中日友好医院,北京100029 [4]山东省泰安市泰山区疾控中心,泰安271000 [5]山东省泰安市中医医院,泰安271000 [6]山东中医药大学附属医院,济南250011

出　　处：《中华中医药杂志》2016年第12期4978-4981,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金面上项目(No.81173245);北京市自然科学基金(重点项目)(No.7121013);中国博士后科学基金资助项目(No.2016M591366)~~

摘　　要：目的:通过研究近十年关于支气管哮喘慢性持续期发病特点的文献,总结其典型临床症状、体征和辨证分型规律,归纳整理支气管哮喘慢性持续期的发病特点。方法:系统检索中英文文献数据库,运用文本挖掘的方法,归纳整理有关支气管哮喘慢性持续期中医证候、症状、体征、舌苔脉象的全部文献;并对以上名称进行规范化,应用IBM SPSS 20.0统计分析其证候、症状及体征、舌苔脉象的分布特点。结果:832篇文献支气管哮喘慢性持续期的4种常见证候为:肺脾两虚、肺肾亏虚、痰热蕴肺、痰湿壅肺;支气管哮喘慢性持续期常见症状如下:1主要症状体征为:咳嗽、喘息、咯痰、胸膈满闷、哮鸣音;2次要症状体征为:乏力,精神倦怠,纳呆,少气懒言,面色晄白,畏风寒,自汗,小便频数,易外感,大便溏,眠差,鼻痒,腰膝酸软,咽痒,喘促气短,喷嚏,声音低怯,口渴,脘腹胀满,耳鸣,痰黏难咳,烦躁,胸疼,呼吸困难,眩晕,抑郁,焦虑;支气管哮喘慢性持续期常见舌象为:舌淡胖,边有齿痕;滑苔;腻苔;厚苔;黄苔;舌暗,有瘀斑。常见脉象为:滑脉、沉脉、细脉、弦脉、虚脉、数脉、实脉、涩脉、弱脉、结脉、濡脉。结论:支气管哮喘慢性持续期涉及多脏腑的功能失调,尤以肺脾为核心,痰饮、瘀血等病理产物共存,呈现本虚标实、寒热错杂的发病特点。Objective： To summarize the characteristics of symptoms, signs and syndrome distribution of chronic persistent bronchial asthma in recent decade by literature research. Methods： The literatures about chronic persistent bronchial asthma from Chinese-English document database were collected, TCM syndromes, symptoms, signs, manifestation of tongue and pulse were systematically summarized with text mining method. All the TCM terms listed above were standardized, the characteristics of syndrome, symptoms and signs were statistical analyzed by IBM SPSS 20.0. Results： Four common syndromes of chronic persistent bronchial asthma were deficiency of both lung and spleen, deficiency of both lung and kidney, phlegm-heat amassing in lung, phlegm-dampness amassing in lung. Common symptoms of chronic persistent bronchial asthma： 1 the main symptoms and signs： coughing, wheezing, coughing up phlegm, chest tightness, wheezing rale. 2Secondary signs and symptoms： fatigue, mental burnout, anorexia, lack of qi and no desire to speak, pale complexion, afraid of cold, spontaneous sweating, frequent urination, easy to catch cold, loose stool, poor sleep, nasal itching, soreness and weakness of waist and knees, pharyngeal itching, shortness of breath, sneezing, low voice, thirsty, abdominal distension, tinnitus, coughing up phlegm difficultly, irritability, chest pain, breathing difficultly, dizziness, depression, anxiety. Common tongue manifestation of bronchial asthma in chronicpersistent period： fat tongue with indentation, slippery fur, greasy fur, thick fur, yellow fur, dark tongue with ecchymosis. Common pulse manifestations sequenced from more to less in proportion： slippery pulse, sunken pulse, thin pulse, wiry pulse, weak pulse, rapid pulse, forceful pulse, hesitant pulse, feeble pulse, knotted pulse, soft pulse. Conclusion： Chronic persistent bronchial asthma involves dysfunction of several zang viscera, especially the lung and spleen, and many pathological product coexistence, such as phlegm and blood stasis

关 键 词：支气管哮喘慢性持续期 发病特点 文献研究 

分 类 号：R259[医药卫生—中西医结合]