中药内服治疗痛风性关节炎规律分析  

Rule analysis of oral administration of Chinese medicine in the treatment of gouty arthritis

作　　者：刘维[1] 刘晴[2] 吴沅皞[1,3] 

机构地区：[1]天津中医药大学第一附属医院,天津300193 [2]天津中医药大学研究生院,天津300193 [3]中国中医科学院中医临床基础医学研究所,北京100700

出　　处：《中华中医药杂志》2016年第12期5178-5181,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81473635;No.81273709);天津市卫生和计划生育委员会中医中西医结合科研课题(No.2015092)~~

摘　　要：目的:总结现代文献中内服中药治疗痛风性关节炎的用药规律。方法:采用计算机检索与人工检索结合的方法,检索1990年1月-2015年7月中国知网全文数据库(CNKI),万方学术期刊全文数据库和维普数据中国内有关内服中药治疗痛风性关节炎的文献进行整理,将纳入文献中的中药用Excel分类整理,设计资料提取表,运用频数、百分数对相关药物进行统计描述。结果:纳入文献272篇,用药207种。出现较多的证型有湿热蕴结证、肝肾阴虚证、湿浊内盛证、痰瘀互结证等。加减用药参考症候较多的是痛甚、热甚、红肿热痛、肿甚。使用频次较高的前10位中药依次为薏苡仁、牛膝、黄柏、苍术、土茯苓、甘草、萆薢、赤芍、威灵仙、泽泻。归类较高的类别为清热药、补虚药、祛风湿药、活血化瘀药、利水渗湿药等。结论:中医治疗痛风性关节炎应辨证论治,注重症状偏重不同,多采用清热祛湿、化瘀通络之法,兼顾扶正祛邪。Objective： To summarize the rules of oral administration of Chinese medicine in the treatment of gouty arthritis in the modern literatures. Methods： The combination of computer-based retrieval and manual retrieve was applied to retrieve CNKI, Wanfang Database and VIP Databases about oral administration of Chinese medicine in the treatment of gouty arthritis from January 1990 to July 2015. The Chinese herbs in included literatures were classified by Excel, and they were analyzed statistically by frequency and percentage. Results： A total of 207 types of Chinese herbs were found in 272 pieces of literatures. Syndromes with high frequency included retention of damp heat, deficiency of both liver and kidney yin, internally exuberant damp turbidity, phlegm and stasis bind. Medicinal symptom with high frequency included pain）, hea, redness, swelling, heat and pain, swelling. Chinese herbs with high frequency included Semen Coicis, Radix Achyranthis Bidentatae, Cortex Phellodendri Chinensis, Rhizoma Atractylodis, Rhizoma Smilacis Glabrae, Radix et Rhizoma Glycyrrhizae, Rhizoma Dioscoreae Hypoglaucae, Radix Paeoniae Rubra, Radix et Rhizoma Clematidis. The majority of them belong to heat-clearing medicinal, deficiency-supplementing medicinal, antirheumatic medicinal, blood-activating and stasis-resolving medicinal, inducing diuresis to drain dampness medicinal. Conclusion： The Chinese medicine treatment of gouty arthritis should be based on syndrome differentiation, and focus on the variety of symptoms. The method of clearing heat and dispelling dampness, resolving stasis and unblocking the collaterals should be mainly used combined with reinforcing the healthy qi and eliminating the pathogenic factors.

关 键 词：痛风性关节炎 中药 规律分析 

分 类 号：R259[医药卫生—中西医结合]