经口内镜下贲门缩窄术治疗胃食管反流病的临床研究  

Peroral endoscopic cardial constriction(PECC) in gastroesophageal reflux disease

作　　者：胡海清[1,2] 柴宁莉[1] 令狐恩强[1] 李惠凯[1] 熊英[1] 张晓彬[1] 支俊丽 王潇潇[1] 艾洁[1] 

机构地区：[1]解放军总医院消化科,北京100853 [2]内蒙古医科大学附属医院消化科,内蒙古010058

出　　处：《中华胃肠内镜电子杂志》2016年第2期65-67,共3页Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition)

基　　金：国家自然科学基金(81370584)

摘　　要：目的一种新的抗反流手术-经口内镜下贲门缩窄术(PECC),探讨其治疗胃食管反流病(GERD)的疗效及安全性。方法选取解放军总医院2014年3月至12月13例接受贲门缩窄术GERD患者进行前瞻性研究,经24 h食管pH监测、食管测压、胃镜检查后接受PECC治疗,随访观察疗效及安全性。结果 13位患者均成功接受了PECC治疗,无严重的治疗相关并发症及死亡病例的发生。研究中PECC治疗后DeMeester评分、pH<4时间百分比、反流次数、长反流次数及长反流持续时间均明显下降。结论经口内镜下贲门缩窄术方法简单、创伤小,近期疗效确实。Objective To explore a new kind of anti-reflux procedures-Peroral Endoscopic Cardial Constriction（PECC） in the treatment of gastroesophageal reflux disease curative effect and safety. Methods In this prospective follow- up study, 13 patients with GERD received PECC from March 2014 to December 2014 at the people＇s liberation army general hospital. The gastroesophageal reflux disease-health related quality of life （GERD-HRQL）scale and esophageal pH monitoring were performed to assess the clinical efficiency at 3 month after PECC treatment, respectively. Results All of the GERD patients received PECC successively and none severe treatment-related complication was reported. DeMeester score and the fraction time of a pH below 4 significantly decreased after PECC treatment. Conclusion PECC is a feasible, safe and effective method to treatment GERD through narrowing the diameter of cardia and preventing the reflux of stomach contents.

关 键 词：经口内镜下贲门缩窄术 胃食管反流病 内窥镜检查 

分 类 号：R655.4[医药卫生—外科学]