磁性分子印迹聚合物的制备与应用研究  

Preparation and application of magnetic molecularly imprinted polymer

作　　者：张曦雯[1] 李兆周[1] 李道敏[1] 陈秀金[1] 高红丽[1] 李智丽[1] 曹力[1] 王耀[1] 侯玉泽[1] 李松彪[1] 吕璞[1] 

机构地区：[1]河南科技大学食品与生物工程学院,河南洛阳471023

出　　处：《化工进展》2016年第12期3964-3969,共6页Chemical Industry and Engineering Progress

基　　金：国家自然科学基金(U1504330);河南科技大学青年学术带头人培养工程;河南科技大学科技创新团队;河南科技大学青年科学基金(2013QN021);河南科技大学创新培育基金(2014ZCX021);河南科技大学大学生研究训练计划(2014118);教育部地方高校国家级大学生创新创业训练计划(201310464007);河南省科技攻关(162102310417);河南省教育厅科学技术研究重点项目(14B550015)

摘　　要：磁性分子印迹聚合物是在磁性微粒表面利用分子印迹技术合成具有超顺磁性、高选择性、高吸附性和特异性识别的聚合物。能在外加磁场作用下实现快速分离和定向移动,是一种新型高分子材料。本文主要介绍了物理法、化学法和模板法3种磁性微粒的制备方法,以及利用分子印迹技术制备磁性分子印迹聚合物,并探讨了悬浮聚合、乳液聚合和沉淀聚合3种聚合方法的研究进展,总结了磁性分子印迹聚合物在农药残留、兽药残留、重金属残留和生物医学方面的应用。分析表明磁性分子印迹聚合物在生物医学领域,尤其是抗菌治疗方面有良好的发展前景。With the features of superparamagnetism,high selectivity,high adsorption and specific recognition,magnetic molecularly imprinted polymer is synthesized by molecular imprinting technique on the magnetic particle surface.Furthermore,it is a new type of polymeric material which achieves rapid separation and directional movement in external magnetic field.This paper describes three preparation methods for magnetic particles,including physical,chemical and templating methods,and molecular imprinting technique for magnetic molecularly imprinted polymer.Additionally,this paper discusses the research progress of the three polymerizations, which are suspension polymerization, emulsion polymerization and precipitation polymerization.Finally,we summarize the applications of magnetic molecularly imprinted polymers in the analyses of pesticide residues,veterinary drug residues,heavy metal residues and biomedicine aspects.It is demonstrated that magnetic molecularly imprinted polymer has great prospects in biomedical science,especially in the treatment of antibacterial disease.

关 键 词：磁性分子印迹技术 聚合物 制备 吸附 

分 类 号：O658.9[理学—分析化学]