2011年-2015年大庆地区解脲脲原体和人型支原体耐药性分析  

Drug resistance analysis of Ureaplasma urealyticum and Mycoplasma hominis in Daqing from 2011 to 2015

作　　者：付宝庆[1] 刘青华[2] 杜静[1] 王金文[1] 张颖[1] 周晓明[1] FU Bao-qing LIU Qing-hua DU Jing WANG Jin-wen ZHANG Ying ZHOU Xiao-ming(Clinical Laboratory, General Hospital of Daqing Oilfield, Daqing, Heilongjiang 163001, China)

机构地区：[1]大庆油田总医院检验科,黑龙江大庆163001 [2]大庆油田总医院感染性疾病科,黑龙江大庆163001

出　　处：《中国卫生检验杂志》2016年第22期3332-3334,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的了解2011年-2015年大庆地区泌尿生殖道感染患者解脲脲原体(Uu)和人型支原体(Mh)感染状况及耐药性变迁。方法采用支原体鉴定试剂盒,对6 851例疑似泌尿生殖道感染标本进行耐药性检测。结果在6 851例标本中,支原体培养阳性3 559例,检出率为51.9%(3 559/6 851)。Uu、Mh及Uu合并Mh感染的阳性率分别为36.9%(2 531/6 851)、2.0%(137/6 851)和13.0%(891/6 851)。Uu合并Mh感染的检出率从2011年的28.8%降低到2015年的4.2%;Uu单独感染的检出率从2011年的33.1%升高到2015年的37.3%;Mh单独感染的检出率一直较低。结论在本地区支原体导致的泌尿生殖道感染主要由Uu引起。临床治疗推荐使用美满霉素、强力霉素、交沙霉素。Objective To investigate the infection and antimicrobial resistance changes of Ureaplasma urealyticum（ Uu） and Mycoplasma hominis（ Mh） in patients with urogenital infections in Daqing from 2011 to 2015. Methods A total of 6 851 specimens were collected from the patients who were suspected of urogenital tract infection for drug resistance test with Mycoplasma identification kit. Results Mycoplasma was identified in 3 559（ 51. 9%） of the 6 851 specimens. Uu alone,Mh alone and Uu plus Mh mixed infections were found respectively in 2 531（ 36. 9%）,137（ 2. 0%） and 891（ 13. 0%）. The detection rate of Uu complicated with Mh infection reduced from 28. 8% in 2011 to 4. 2% in 2015; the detection rate of Uu infection alone increased from 33. 1% in 2011 to 37. 3% in 2015; the detection rate of Mh infection alone had always been low. Conclusion The urogenital tract infection caused by Mycoplasma is predominantly due to Uu. Minocycline,Doxycycline and Josamycin should be recommended for clinical treatment of such infections.

关 键 词：解脲脲原体 人型支原体 抗菌药物 耐药性 

分 类 号：R518.9[医药卫生—内科学]