夫妻均为HBeAg阳性慢性乙型肝炎患者围生期全程抗病毒阻断垂直传播1例报道  

Vertical transmission of HBV was interrupted by antiviral therapy to the chronic hepatitis B couple both with HBeAg-positive during the whole perinatal period: a case report

作　　者：赵琴[1,2] 雷旭[1] 刘园园[1] 谭华炳[1] 贺琴[1] 

机构地区：[1]湖北医药学院附属人民医院肝病研究所药学部,湖北十堰442000 [2]湖北房县人民医院检验科,湖北房县442100

出　　处：《中国肝脏病杂志（电子版）》2016年第3期120-122,共3页Chinese Journal of Liver Diseases：Electronic Version

摘　　要：本文报道1对夫妻均为HBeAg阳性慢性乙型肝炎患者,通过围生期全程替比夫定抗病毒治疗,婴儿实施乙肝免疫球蛋白联合乙肝疫苗免疫,成功阻断乙型肝炎病毒母婴传播的病例。提示抗病毒治疗作为传统母婴传播阻断技术的补充,具有重要临床意义。This paper reported one case that HBV transmission from chronic hepatitis B mother to infant was interrupted successfully by antiviral therapy with telbivudine to the couple who with HBeAg-positive during the whole perinatal period and hepatitis B immune globulin combined hepatitis B vaccine was given to the baby. It reminds that antiviral therapy to supplemented the traditional prevention of mother-to- child transmission has clinical significance.

关 键 词：肝炎 乙型 慢性 夫妻 母婴传播阻断 随访 

分 类 号：R512.62[医药卫生—内科学]