冠心病痰热互结证与血清hs-CRP、IL-6水平相关性研究  

Association between coronary heart disease with intermingled phlegm-heat syndrome and serum levels of high-sensitivity C-reactive protein and interleukin-6

作　　者：曹楚珩 阮浩坤 龙雨[1] 罗尧岳[1] CAO Chu- heng RUAN Hao- kun LONG Yu LUO Yao- yue(Hunan University of Chinese Medicine, Changsha 410208, Hunan, China Shangyu Hospital of Traditional Chinese Medicine, Shaoxing 312300, Zhejiang, China)

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]浙江省绍兴市上虞中医医院,浙江绍兴312300

出　　处：《湖南中医杂志》2016年第11期10-12,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：湖南中医药大学中医诊断国家重点学科开放基金资助(编号:2013ZYZD22)

摘　　要：目的:探讨冠心病痰热互结证与血清超敏C反应蛋白(hs-CRP)、白介素-6(IL-6)水平的相关性。方法:将诊断为冠心病痰热互结证患者34例、冠心病气虚血瘀证患者30例、健康居民26例分为3组,空腹取静脉血,采用免疫透射比浊法检测血清hs-CRP水平、放射免疫分析法检测血清IL-6水平。结果:冠心病痰热互结组血清hs-CRP、IL-6的水平高于冠心病气虚血瘀组和对照组,差异均有统计学意义(P<0.01)。结论:血清hs-CRP、IL-6的水平与冠心病痰热互结证有一定的相关性。Objective： To investigate the association between coronary heart disease（ CHD） with intermingled phlegm-heat syndrome and serum levels of high-sensitivity C-reactive protein（ hs-CRP） and interleukin-6（ IL-6）. Methods： A total of 34 CHD patients with intermingled phlegm-heat syndrome,30 CHD patients with qi-deficiency and blood-stasis syndrome,and 26 healthy residents were enrolled as three groups. Fasting venous blood samples were collected,and turbidimetric immunoassay and radioimmunoassay were used to measure the serum levels of hs-CRP and IL-6,respectively. Results： The intermingled phlegm-heat syndrome group had significantly higher serum levels of hs-CRP and IL-6 than the qi-deficiency and blood-stasis syndrome group and the control group（ P 〈0. 01）. Conclusion： There is certain association between serum levels of hs-CRP and IL-6 and coronary heart disease with intermingled phlegm-heat syndrome.

关 键 词：冠心病 痰热互结证 HS-CRP IL-6 

分 类 号：R259.414[医药卫生—中西医结合]