纤维支气管镜介入治疗耐多药肺结核临床效果观察  

Observation of clinical effect by bronchofibroscope interventional therapy for multi-drug resistant tuberculosis

作　　者：江万航[1] 杜正新[1] 何敬业[1] 谭俊豪[1] JIANG Wan-hang DU Zheng-xin HE Jing-ye et al(Guangzhou City Chest Hospital, Guangzhou 510095, China)

机构地区：[1]广州市胸科医院,510095

出　　处：《中国实用医药》2016年第30期3-5,共3页China Practical Medicine

摘　　要：目的对耐多药肺结核患者进行纤维支气管镜介入治疗,分析其临床效果。方法 100例耐多药肺结核患者,随机分为观察组和对照组,各50例。对照组患者采用耐多药方案6Z Am Lfx PAS Pto/18Z Lfx PAS Pto治疗,观察组在对照组治疗基础上联合纤维支气管镜介入治疗。对比两组患者的临床治疗效果。结果治疗6个月后,观察组痰菌转阴率明显优于对照组(P<0.05);观察组病灶显效率、空洞闭合率分别为90.00%、88.00%,均优于对照组的74.00%、70.00%,差异均具有统计学意义(P<0.05)。结论纤维支气管镜介入治疗耐多药肺结核,临床效果显著,不良反应较少。Objective To apply bronchofibroscope interventional therapy for multi-drug resistant tuberculosis patients, and to analyze clinical effect. Methods A total of 100 patients with multi-drug resistant tuberculosis were randomly divided into observation group and control group, with 50 cases in each group. The control group received multi-drug resistant scheme 6Z Am Lfx PAS Pto/18 Z Lfx PAS Pto for treatment, and the observation group also received additional bronchofibroscope interventional therapy. Clinical effects were compared between the two groups. Results After 6-month treatment, the observation group had much lower sputum negative conversion rate than the control group（P〈0.05）; and it also had better lesion excellent rate and cavity closure rate as 90.00% and 88.00% than 74.00% and 70.00% of the control group. Their differences all had statistical significance（P〈0.05）. Conclusion Bronchofibroscope interventional therapy shows remarkably clinical effect and few adverse reactions in treating multi-drug resistant tuberculosis.

关 键 词：纤维支气管镜介入 耐多药肺结核 临床效果 观察 

分 类 号：R521[医药卫生—内科学]