铁调素与慢性心力衰竭合并贫血关系的研究进展  

Research progress in the relationship between hepcidin and chronic heart failure complicated with anemia

作　　者：刘晶[1] 李英梅[1] 

机构地区：[1]上海中医药大学附属普陀医院,上海200062

出　　处：《中国临床医学》2016年第5期684-686,共3页Chinese Journal of Clinical Medicine

基　　金：上海市卫生和计划生育委员会面上项目(201540264);上海市普陀区科学技术委员会自主创新项目(2013PTKW021)~~

摘　　要：铁调素是近年来发现的一种负性调节血清铁浓度的激素,有助于维持机体内铁代谢的动态平衡。铁调素代谢紊乱可以导致血红蛋白降低等多种与铁代谢异常相关的病证。贫血是慢性心力衰竭患者的常见并发症,其与铁代谢异常紧密相关。近年来,随着铁调素在铁代谢中的重要作用被发现,铁调素与慢性心力衰竭合并贫血发生发展的紧密联系也逐渐受到重视。Hepcidin,a hormone discovered in recent years that can negatively regulate serum iron concentration,helps to maintain the dynamic balance of iron metabolism in the body.Hepcidin metabolic disorder can lead to the reduction of hemoglobin and other diseases associated with abnormal iron metabolism.Anemia is a common complication in patients with chronic heart failure,which is closely related to abnormal iron metabolism.As the important role of hepcidin in iron metabolism is found in recent years,the close relationship between hepcidin and chronic heart failure complicated with anemia has also been found gradually.

关 键 词：铁调素 铁代谢 慢性心力衰竭 贫血 

分 类 号：R541.6[医药卫生—心血管疾病]