大剂量地塞米松联合rhTPO治疗初治重症原发免疫性血小板减少症疗效观察  

Effect Observation of High-dose Dexamethasone and rh TPO on Initial Treatment Severe ITP

作　　者：魏炜[1] 

机构地区：[1]上海交通大学医学院附属苏州九龙医院血液科,江苏苏州215024

出　　处：《中国继续医学教育》2016年第33期202-204,共3页China Continuing Medical Education

摘　　要：目的观察大剂量地塞米松结合rh TPO治疗初治原发免疫性血小板减少症（ITP）的疗效。方法选取我院2014年1月~2016年7月收治的初治重症ITP患者40例,随机分为两组,对照组及观察组,各20例,两组患者均给予地塞米松,观察组在此基础上加用rh TPO。观察两组患者疗效及不良反应发生情况。结果观察组治疗总有效率（75%）高于对照组（30%）,差异有统计学意义（P〈0.05）;观察组不良反应总发生率（15%）低于对照组（20%）,差异无统计学意义（P〉0.05）。结论rhT PO结合大剂量地塞米松治疗初治ITP临床疗效好,且患者治疗过程中不良反应发生情况少。Objective To investigate the clinic effect of high-dose dexamethasone and rh TPO on initial treatment severe ITP. Methods 40 cases with ITP in our hospital from January 2014 to July 2016 were selected and divided into control group and observation group, 20 cases in each group. They were all given dexamethasone and observation group was added with rh TPO. Observe the effect and adverse reactions of the two groups. Results Total efficiency of observation group（75%） was higher than control group（30%）, the difference was statistically significant（P〈0.05）, adverse reaction rate of observation group（15%） was lower than control group（20%）, the difference was not statistically significant（P〈0.05）. Conclusion High-dose dexamethasone and rh TPO has significant effect on initial treatment severe ITP, adverse reactions is less during treatment.

关 键 词：地塞米松 RHTPO ITP 治疗疗效 

分 类 号：R558[医药卫生—血液循环系统疾病]