动脉导管未闭结扎术中扩血管药物的选择与对比研究  

Study on the Selection and Comparison of Drugs for the Expansion of Blood Vessels in PDA Ligation

作　　者：房丽华 赵越 姜颀 王振坤 

机构地区：[1]黑龙江省哈尔滨市儿童医院麻醉科,黑龙江哈尔滨150010

出　　处：《中国继续医学教育》2016年第32期158-159,共2页China Continuing Medical Education

摘　　要：目的 对比不同血管扩张药物在动脉导管未闭（PDA）结扎术中的应用效果。方法 选取我院收治的20例患儿作为研究对象,随机分为A组、B组,每组各10例,所有患儿均行左外侧开胸手术,分离动脉导管,常规降压后,丝线结扎。A组给予硝酸甘油,B组采用法舒地尔,用法与A组基本相同,3-5 ng/（kg·min）持续泵入,调节泵入速度。结果 治疗后24 h,与治疗前对比,A组、B组cTnT、CK-MB均高于术前,且A组患者cTnT、CK-MB均高于B组,差异有统计学意义（P〈0.05）,手术成功率100%。结论 PDA结扎术中应用法舒地尔有助于减轻心肌损伤。Objective To compare the effect of different blood vessel dilation drugs in the ligation of patent duct （PDA）.Methods 20 cases wereselected as the research object and were randomly divided into A group and B group, 10 cases in each group. All patients underwent left lateral thoracotomy, isolated artery catheter, conventional blood pressure after ligation. A group was given about nitroglycerin, B group were treated with fasudil. A groups were basically the same, 3 - 5 ng/（ kg·min） pump, pump speed adjustment.Results 24 h after treatment, compared with before treatment, A group, B group CK-MB, cTnT were higher than preoperative, and A group of patients with CK-MB, cTnT were higher than the B group, the difference was statistically significant （P〈0.05）. The success rate of operation was 100%.Conclusion Application of fasudil ligation of PDA helps alleviate the myocardial injury.

关 键 词：PDA结扎术 扩血管药物 心肌损 

分 类 号：R614[医药卫生—麻醉学]