国内新出现的基因7型Ⅰ类新城疫病毒的分离与鉴定  

Isolation and identification of new emerging genotype 7 of class Ⅰ Newcastle disease virus

作　　者：刘华雷[1] 吕艳[1] 王静静[1] 郑东霞[1] 赵云玲[1] 王志亮[1] LIU Hua-lei LYU YanA WANG Jing-jing ZHENG Dong-xia ZHAO Yun-ling WANG Zhi-liang(China Animal Health and Epidemiology Center ,Qingdao,Shandong 266032,Chin)

机构地区：[1]中国动物卫生与流行病学中心,山东青岛266032

出　　处：《中国兽医学报》2016年第12期1997-2000,共4页Chinese Journal of Veterinary Science

基　　金：国家公益性行业(农业)科研专项资助项目(201303033)

摘　　要：在主动监测中从广西活禽市场的家鸭中分离到1株Ⅰ类新城疫病毒,遗传进化分析证实该分离株属于基因7型(按照Diel DG的分类方法则属于基因1c亚型)。该分离株在裂解位点的氨基酸组成为112 ERQERL117,具有典型低致病性新城疫病毒的分子特征。这是我国首次检出基因7型Ⅰ类新城疫病毒,对于其来源和分布需要进一步加强监测和研究。One class Ⅰ Newcastle disease virus was isolated from domestic ducks in live bird mar- kets of Guangxi province during the active surveillance. Phylogenetic analysis revealed that the iso- late belonged to genotype 7 （or genotype lc based on Did DG^s classification system）. The virus has the motif U2ERQERL117 at the cleavage site of the fusion protein,which is typical of lentogenic NDV strains. This is the first report on genotype 7 in China. Further studies need to be done in order to clarify the origin and distribution of this kind of virus.

关 键 词：新城疫病毒 Ⅰ类 基因7型 家鸭 

分 类 号：S852.65[农业科学—基础兽医学]