沙门菌分泌系统研究进展  

Research progress on Salmonella secretion systems

作　　者：安树敏 郭荣显 耿士忠 薛颖 潘志明 焦新安 AN Shu-min GUO Rong-xian GENG Shi-zhong XUE Ying PAN Zhi-ming JIAO Xin-an(Key Laboratory of Zoonoses of Jiangsu Province ,Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses of Jiangsu Province ,Yangzhou University, Yangzhou ,Jiangsu 225009 ,Chin)

机构地区：[1]扬州大学江苏省人兽共患病学重点实验室/江苏省动物重要疫病与人兽共患病防控协同创新中心,江苏扬州225009

出　　处：《中国兽医学报》2016年第12期2176-2182,共7页Chinese Journal of Veterinary Science

基　　金：国家"863"计划资助项目(2011AA10A212);国家自然科学基金资助项目(31230070);江苏省自然科学基金资助项目(BK20151306);中国博士后基金资助项目(2014-M551670)

摘　　要：目前已知革兰阴性菌的分泌系统共有6种类型,然而在沙门菌中只发现其中5种,即Ⅰ型、Ⅲ型、Ⅳ型、Ⅴ型和Ⅵ型分泌系统,对Ⅱ型分泌系统却未见报道。沙门菌的许多生物学特性是依赖于其分泌系统实现的,通过这些分泌系统,分泌性蛋白质或毒素被转运到细菌胞外,与宿主细胞发生相互作用而发挥其致病性。Six major secretion systems have been characterized for Gram negative bacteria, from type Ⅰto type Ⅵ. Whereas,only five secretion systems exist in Salmonella,but no report on type Ⅱsecretion system. Many physiological functions of Salmonella are implemented by secretion systems. Through these secretion systems, many secretory proteins and toxins are transported to the outside of bacterial cells,interacting with host cells to exert their toxicity.

关 键 词：沙门菌 革兰阴性菌 分泌系统 

分 类 号：S852.61[农业科学—基础兽医学] S855.99[农业科学—兽医学]