极低／超低出生体质量儿812例住院情况单中心回顾性研究  

A single center retrospective study on hospitalization information for 812 cases of very low birth weight and extremely low birth weight infants

作　　者：张漪[1] 陈样[1] 夏世文[1] 

机构地区：[1]湖北省妇幼保健院新生儿科,武汉430070

出　　处：《中华实用儿科临床杂志》2016年第23期1822-1825,共4页Chinese Journal of Applied Clinical Pediatrics

摘　　要：目的分析极低出生体质量儿和超低出生体质量儿住院情况及结局。方法以湖北省妇幼保健院新生儿科作为单中心研究，回顾性分析该院2009年1月至2014年12月住院的812例出生体质量（BW）〈1500g患儿的围生期情况、治疗经过、并发症等住院情况，分析比较各相关资料对住院结局的影响。结果1.结局良好者621例，占76.5%。2.不同BW组间及不同胎龄（GA）组间结局良好率比较差异均有统计学意义（χ^2=28.87、14.77，P均〈0.05）；男性患儿、产妇17～25岁和36～46岁年龄组的患儿，产前使用糖皮质激素者，无宫内感染者，母亲无妊娠高血压病者，母亲无妊娠期糖尿病患儿结局良好率高于相应对照组，差异均有统计学意义（χ^2=4.69、11.19、8.02、8.61、7.20、19.20，P均〈0.05）。3.使用中心静脉置管（PICC）的患儿及10 d内恢复BW的患儿结局良好率均高于相应对照组，差异均有统计学意义（χ^2=33.31、29.65，P均〈0.05）。4.并发脑室内出血（IVH）、呼吸窘迫综合征（RDS）、坏死性小肠结肠炎、重度窒息患儿结局良好率低于对照组，差异均有统计学意义（χ^2=13.16、7.59、13.02、6.05，P均〈0.05）。5.Logistic回归分析示：低BW、GA小、出生较早、未使用PICC、产前未使用糖皮质激素、重度窒息、IVH、RDS是影响预后的危险因素（P均〈0.05）。结论极低/超低出生体质量儿结局良好率逐步提高，且与GA、BW、母亲年龄、围生期保健、并发症、治疗技术及社会因素等密切相关。ObjectiveTo analyze the survival rate and hospitalization information for 812 cases of very low birth weight （VLBW） and extremely low birth weight （ELBW） infants.MethodsThe retrospective study was conducted in a single center, Department of Neonatology, Hubei Women and Children Hospital, from January 2009 to December 2014, where the data of 812 infants with birth weight（BW） less than 1 500 g was analyzed in regard to perinatal condition, treatment and complications of these in relation to prognosis.Results（1）A total of 621 cases（76.5%） had favorable prognosis.（2）There was a significant difference in the favorable prognosis rate between different BW groups （χ^2=28.87, P〈0.05） and different gestational age（GA） groups （χ^2=14.77, P〈0.05）. The favorable prognosis rate for the male infants（χ^2=4.69, P〈0.05）, puerpera age between 17-25 and 36-46 years old （χ^2=11.19, P〈0.05）, usage of prenatal hormones（χ^2=8.02, P〈0.05）, the infants without intrauterine infection （χ^2=8.61, P〈0.05）, the mother without gestational hypertension （χ^2=7.20, P〈0.05） and gestational diabetes mellitus（χ^2=19.2, P〈0.05） were different compared to the control groups.（3）Infants with peripherally inserted central catheter （PICC） （χ^2=33.31, P〈0.05）and recovery birth weight within 10 days（χ^2=29.65, P〈0.05） had higher favorable prognosis rate compared to the control groups, which had significant differences.（4）Infants with intraventricular haemorrhage （IVH）（χ^2=13.16, P〈0.05）, respiratory distress syndrome （RDS）（χ^2=7.59, P〈0.05）, necrotizing enterocolitis （NEC）（χ^2=13.02, P〈0.05） and serious asphyxia （χ^2=6.05, P〈0.05）had lower favorable prognosis rates than those did not, with significant differences.（5）Logistic analysis： the lower BW, smaller GA, earlier birth, unused PICC, serious asphyxia, IVH, RDS were risk factors for poor prognosis（all P〈0.05）.ConclusionsThe favorable prognosis ra

关 键 词：极低出生体质量儿 超低出生体质量儿 结局良好率 救治情况 单中心研究 

分 类 号：R722.6[医药卫生—儿科]