导管介入治疗小儿先天性心脏病的疗效分析  

The Curative Effect of Catheter Interventional Treatment of Pediatric Congenital Heart Disease

作　　者：林惠泉[1] 蓝雅琼[1] 郑燕红 蔡海明[1] 

机构地区：[1]福建医科大学附属漳州市医院儿科,福建漳州363000 [2]解放军第一七五医院药学科,福建漳州363000

出　　处：《医学综述》2016年第22期4493-4495,4499,共4页Medical Recapitulate

摘　　要：目的分析导管介入治疗小儿先天性心脏病的疗效。方法选取2011年7月至2014年1月福建医科大学附属漳州市医院收治的先天性心脏病患儿130例,按照抽签法分为观察组和对照组,各65例。对照组行传统的开胸手术治疗,观察组行导管介入治疗。观察两组患儿术前、术后3个月的心胸比率、心腔变化、左心收缩功能的变化,并评价治疗3个月后的疗效以及预后效果。结果观察组患儿的手术成功率高于对照组[96.92%(63/65)比87.69%(57/65),P<0.05]。术后48 h,观察组患儿的心胸比率显著低于对照组[(0.49±0.02)%比(0.55±0.05)%],差异有统计学意义(P<0.01)。术后3个月,观察组的左心房内径、左心室舒张末期内径、左心室收缩末期内径、右心室直径显著小于对照组[(22.7±4.3)mm比(25.4±3.4)mm、(31.2±3.2)mm比(35.4±3.4)mm、(17.5±3.4)mm比(20.5±3.1)mm、(12.2±1.4)mm比(15.0±2.6)mm](P<0.01)。术后3个月,观察组患儿的左心室每搏量显著高于对照组[(66.2±5.6)m L比(61.2±6.7)m L](P<0.01)。观察组的总并发症发生率显著低于对照组[4.76%(3/63)比19.30%(11/57),P<0.05]。结论导管介入治疗小儿先天性心脏病效果显著,术后成功率高,且预后较好。Objective To analyze the curative effect of catheter interventional treatment of pediatric congenital heart disease. Methods Total of 130 children with congenital heart disease in Zhangzhou Hospital Affiliated to Fujian Medical University from Jul. 2011 to Jan. 2014 were included in the study,according to the sortition method they were divided into an observation group and a control group,65 cases in each group. The control group was treated with traditional open heart surgery,while the observation group was treated with catheter interventional treatment. Before surgery and postoperative 3 months,the cardiothoracic ratio,heart cavity change,the change of left cardiac systolic function of the two groups were observed,and the effect of the treatment and prognosis was evaluated 3 months after treatment. Results The surgery success rate of the observation group was higher than the control group[96. 92%（ 63 /65） vs 87. 69%（ 57 /65）,P 0. 05]. At 48 h after surgery,cardiothoracic ratio of the observation group was significantly lower than the control group[（ 0. 49 ± 0. 02） % vs（ 0. 55 ± 0. 05） % ]（ P 0. 01）. The left atrium diameter,left ventricular end-diastolic,left ventricular systolic diameter,right ventricular diameter at the end of the of the observation group were less than the control group [（ 22. 7 ± 4. 3） mm vs（ 25. 4 ± 3. 4） mm,（ 31. 2 ± 3. 2） mm vs（ 35. 4 ± 3. 4） mm,（ 17. 5 ± 3. 4） mm vs（ 20. 5 ± 3. 1） mm,（ 12. 2 ± 1. 4） mm vs（ 15. 0 ± 2. 6） mm]（ P 〈0. 01）,the left ventricular stroke volume was higher than the control group [（ 66. 2 ± 5. 6） m L vs（ 61. 2 ± 6. 7） m L]（ P 〈0. 01）,complication rate of the observation group was lower than the control group[4. 76%（ 3 /63） vs 19. 30%（ 11 /57）,P 〈0. 05]. Conclusion Catheter interventional treatment of pediatric congenital heart disease has remarkable effect,with high success rate and good prognosis.

关 键 词：小儿先天性心脏病 导管介入治疗 开胸手术 

分 类 号：R815[医药卫生—放射医学]