血浆D二聚体在卵巢过度刺激综合征患者治疗中的临床意义  

Variation of Plasma D-dimers in Patients with Ovarian Hyperstimulation Syndrome

作　　者：刘程[1] 周桂香[1] 倪丹[1] 许波[1] 刘雨生[1] 

机构地区：[1]安徽医科大学附属省立医院,合肥230001

出　　处：《临床输血与检验》2016年第6期574-576,共3页Journal of Clinical Transfusion and Laboratory Medicine

基　　金：国家自然科学基金青年项目(No.81601244)资助

摘　　要：目的探讨血浆D二聚体在卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS)患者治疗中的改变,为临床治疗提供指导意义。方法回顾性分析安徽省立医院生殖医学中心75例体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)后因OHSS住院治疗患者的临床资料,分析患者治疗前、后血浆D二聚体的差异。结果75例中重度OHSS患者经积极纠正血液浓缩、纠正低蛋白血症、预防血栓形成治疗后,在入院日D二聚体、出院日D二聚体的差异有统计学意义(P<0.05)。结论动态检测OHSS患者治疗过程中血浆D二聚体的变化,对评估其临床治疗及判断预后有指导意义。Objective To investigate the change of plasma D-dimers during the treatment of patients with ovarian hyperstimulation syndrome,and to discuss the clinical significance of monitoring D-dimer levels.Methods The clinical data of75 inpatients were analyzed retrospectively（from July2015 to June2016） who suffered from OHSS following IVF-ET. Paired T tests were used to reveal the D-dimer level of patients before and after treatment.Results A statistical significance of plasma D-dimer levels was noted between the patients with OHSS on admission and those discharged from hospital（P〈0.05）.Conclusion Monitoring the D-dimer level of patients with OHSS during the treatment,is of significance in evaluation of treatments and prognosis.

关 键 词：卵巢过度刺激综合征 体外受精-胚胎移植 D二聚体 

分 类 号：R588.6[医药卫生—内分泌] R446.11[医药卫生—内科学]