PKP与PVP治疗轻中度骨质疏松性椎体压缩性骨折的临床疗效比较  

Treatment of mild to moderate osteoporotic vertebral compression fractures by percutaneous vertebroplasty versus percutaneous balloon kyphopalasty

作　　者：王振斌[1] 涂来勇[1] 顾文飞[1] 赵疆[1] 卡哈尔.艾肯木 

机构地区：[1]新疆医科大学附属中医医院脊柱一科,乌鲁木齐830000

出　　处：《浙江医学》2016年第23期1896-1898,1905,共4页Zhejiang Medical Journal

基　　金：新疆维吾尔自治区自然科学基金资助项目(2016D01C139)

摘　　要：目的探讨经皮椎体成形术(PVP)与经皮球囊扩张椎体成形术(PKP)治疗轻中度骨质疏松性椎体压缩性骨折(OVCFs)的临床疗效。方法回顾性分析48例轻中度OVCFs患者的临床资料,其中行PVP25例,PKP23例;比较两组患者手术前后Cobb’s角、椎体前缘高度、视觉模拟评分(VAS)、活动功能评分、并发症和治疗费用等情况。结果两组患者手术前后Cobb's角、椎体前缘高度、VAS、活动功能评分比较,差异均有统计学意义(均P<0.05),其中术后3d、术后3个月和术后6个月均较术前明显好转(均P<0.05)。两组患者术后并发症比较,差异无统计学意义(P>0.05);治疗费用比较,PKP组明显高于PVP组(P<0.05)。结论PVP与PKP治疗轻中度OVCFs的临床疗效相当,从治疗成本考虑,建议优先应用PVP。Objective To compare the clinical effects of percutaneous vertebroplasty（PVP） and percutaneous balloon kyphopalasty（PKP） in treatment of mild to moderate osteoporotic vertebral compression fractures（OVCFs）. Methods The clinical data 48 patients with mild to moderate OVCFs treated with PKP（n=25） or PVP（n=23） from January 2010 to February 2015 were retrospectively analyzed. The VAS scores, vertebral leading edge altitude, Cobb＇s angle, preoperative and postoperative activity of daily life, postoperative complications and medical costs were compared between two groups. Results The patients were followed up for 14.00±3.25 months（range 1-27 months）. The VAS scores, vertebral leading edge altitude, Cobb＇s angle,activity of daily life were significantly improved 3 days, 3 months, 6 months after treatment in both groups（P〈0.05）. There was no significant difference in postoperative complications between PKP group and PVP group（P〉0.05）. The medical coast of PKP was significantly higher than that of PVP（P〈0.05）. Conclusion There are no differences in curative effect for mild to moderate osteoporotic vertebral compression fractures between PKP and PVP, however, the medical cost of PVP is lower.

关 键 词：经皮椎体成形术 经皮球囊扩张椎体成形术 椎体压缩性骨折 骨质疏松 

分 类 号：R580[医药卫生—内分泌] R687.3[医药卫生—内科学]