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机构地区:[1]山东中医药大学,济南250355
出 处:《中国实验方剂学杂志》2016年第23期187-191,共5页Chinese Journal of Experimental Traditional Medical Formulae
基 金:山东省自然科学基金项目(ZR2015HM056)
摘 要:目的:基于中医传承辅助平台(V2.5)软件,分析刘持年教授治疗青年人高血压的用药经验。方法:收集刘持年教授临证中用于治疗青年人高血压的医案,筛选处方用药,录入中医传承辅助平台软件,进行相应的数据挖掘,分析刘持年教授治疗青年人高血压的用药经验。结果:对筛选出的60首处方进行相关规则分析,挖掘药物的使用频次及药物之间的关联规则,结果得出16个核心组合和8首新处方。结论:刘持年教授治疗青年人高血压注重初期以实为主,渐至虚实互见的病理变化,分清阴虚与阳亢的主次轻重,以清肝泻火、疏肝理气、平肝潜阳等作为处方的主要立法依据,同时注重养肝柔肝,顾护肝阴。中医传承辅助平台对于分析名老中医处方用药规律具有实用性、客观性,对科学全面地总结名老中医的临床经验具有重要的价值。Objective: To analyze the medication experience of Professor LIU Chi-nian for treating young people with hypertension by using Traditional Chinese Medicine( TCM) Inheritance Support System.Method: The prescriptions for treating young people with hypertension were collected,and input into TCM Inheritance Support System. The composing principles were analyzed by using data mining methods,such as revised mutual information,complex system entropy cluster and unsupervised hierarchical cluster. Result: Based on the analysis on 60 prescriptions,the frequency of each herb and association rules among the herbs were determined,16 core combinations and 8 new prescriptions were mined from the database. Conclusion: Professor LIU Chi-nian focused on the different-stage treatment for young people with hypertension. There are more excess syndromes and less deficiency syndromes in the early stage,which turned into the combination of both with the pathologic changes. According to the stages of the disease,we should distinguish Yin deficiency and Yang excess syndrome. Professor LIU Chi-nian made prescriptions on the basis of clearing liver and clearing liver fire,soothing the liver and regulating Qi,and suppressing hyperactive liver and subsiding Yang. At the same time,professor LIU Chi-nian attached great importance to nourishing and smoothing the liver,and protecting liver Yin. The TCM Inheritance Support System is practical and objective to analyze the TCM doctor' medication experience,and has important value to summarize his clinical experience in a scientific and all-round manner.
关 键 词:刘持年 青年人高血压 用药规律 中医传承辅助平台(V2.5)
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