3D打印辅助上颌骨切除术后缺损重建  

Application of three-dimensional printing technique in assisting reconstruction after maxillectomy

作　　者：吴昆旻[1,2] 吴建[1] 李泽卿[2] 陈伟 朱春晖[2] 杨祁[2] 

机构地区：[1]第二军医大学附属长征医院耳鼻咽喉科,上海200003 [2]南京中医药大学第二附属医院耳鼻咽喉科,江苏南京210017 [3]南京总医院耳鼻咽喉科,江苏南京210002

出　　处：《山东大学耳鼻喉眼学报》2016年第6期29-32,36,共5页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：上海市科学技术委员会西医引导重点科研项目(14411960400;14411960401);上海市科学技术委员会产学研重点项目(14DZ1940103)

摘　　要：目的 探讨3D打印技术在上颌窦恶性肿瘤外科治疗中的可行性和应用效果。方法 对5例因上颌窦恶性肿瘤行手术治疗的患者,根据术前CT扫描数据,应用3D打印技术打印出患侧上颌窦的树脂模型,在此模型上对钛网进行塑形,制备出个性化钛网,将个性化钛网植入缺损区。通过临床和CT检查,评价其颌面部外形与功能。结果 所有病例手术顺利,颌面部外形恢复良好,两侧对称,未见复视及眼球内陷,植入的钛网与缺损周边骨床贴合紧密。术后随访8~30个月,经临床和CT检查未见肿瘤复发。结论 3D打印技术在上颌窦恶性肿瘤的外科治疗中具有较好的可行性和可靠性,可提高上颌窦恶性肿瘤手术治疗的精确性及临床治疗效果。Objective To investigate the application and clinical outcomes of 3-Dcomputer-assisted printing technique in the surgical treatment of malignant tumors of maxillary sinus. Methods Five patients suffering from malignant tumors of maxillary sinus received total maxillectomy were included in this study, Before operation, a three-dimensional individual stereo-maxillary model based on mirror images of the unaffected maxilla was obtained to fabricate an anatomically adapted titanium mesh using computer-assisted design and manufacturing. The individual titanium mesh was inserted into the maxillary after total maxillectomy. Facial appearance and function were evaluated by clinical and CT examinations. Results All patients were satisfied with their postoperative facial symmetry and did not develop diplopia or endophthalmos. During the operation procedure, the pre-bent titanium mesh did not require reshaping and pruning. The implanted titanium mesh fit bone bed surrounding the defect closely. Clinical and CT examinations showed recurrence in none during the follow-up of 8 to 30 months. Condusion With good feasibility and reliability, 3-dimensional printing technique is suitable for the surgical treatment of maxillary sinus malignant tumors, and can significantly improve the clinical outcome.

关 键 词：上颌骨切除 3D打印技术 钛网 重建术 

分 类 号：R765.9[医药卫生—耳鼻咽喉科]