替考拉宁治疗卒中后耐药球菌肺炎的临床观察  

Clinical observation on teicoplanin treated resistant cocci pneumonia after stroke

作　　者：魏风芹[1] 赵伟业[1] 刘学东[1] 刘菁[1] 吕森森[1] WEI Feng-qin ZHAO Wei-ye LIU Xue-dong LIU Jing LYU Sen-sen(Qingdao Municipal Hospital, Qingdao, Shandong 266003, Chin)

机构地区：[1]青岛市市立医院呼吸科,山东青岛266003

出　　处：《中华医院感染学杂志》2016年第23期5382-5384,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(81571938)

摘　　要：目的探讨替考拉宁对脑卒中后耐药革兰阳性菌肺炎的临床疗效、安全性及细菌清除率,为临床治疗提供参考依据。方法回顾2013年11月-2015年11月30例脑卒中后感染耐药球菌的肺炎患者,均有不同程度的基础疾病,给予替考拉宁0.4g,溶于0.9%氯化钠100ml,12h/次,3次后改为24h/次,疗程为7~14d,观察患者的临床症状及体征、辅助检查结果、细菌清除率及不良反应,并对其进行分析及评价。结果替考拉宁治疗后有效率83.33%,细菌清除率83.33%,不良反应率6.67%。结论替考拉宁治疗脑卒中后耐药革兰阳性菌性肺炎疗效好,安全性高,不良反应少。OBJECTIVE To discuss clinical efficacy,safety,and the bacterial clearance rate of teicoplanin in the treatment of drug-resistant cocci pneumonia after stroke,so as to provide reference for clinical treatment.METHODS From Nov.2013 to Nov.2015,a total of 30 patients with drug-resistant cocci pneumonia after stroke and with certain level of underlying disease were under retrospectively studied.Teicoplanin 0.4g dissolving in 100 ml 0.9% sodium chloride 12 hours once was provided.After 3times,it changed to 1time 24 hours a day,period of treatment for 7to 14 days.The patient′s clinical symptoms and signs,auxiliary examination results,bacterial clearance rate and adverse reactions were under observation,and carried on the analysis and evaluation.RESULTS The treatment efficient was 83.33%,the bacteria clearance rate was 83.33%,and the adverse reaction rate was6.67%.CONCLUSIONTeicoplanin treats resistant cocci pneumonia after stroke having good curative effect,high safety,less adverse reaction.

关 键 词：替考拉宁 卒中后肺炎 耐药革兰阳性菌 

分 类 号：R978.1[医药卫生—药品]