心脏再同步化治疗患者双室同步起搏与左心室内同步化的相关性  

Correlation between double ventricular synchronous pacing and left ventricular systolic synchronicity after cardiac resynchronization therapy

作　　者：刘博[1] 张勇[1] 徐晶[1] 姜馨[1] 李尚俭[1] 马爱群[2] 

机构地区：[1]陕西省人民医院心内科,陕西西安710068 [2]西安交通大学第一附属医院心内科,陕西西安710061

出　　处：《心脏杂志》2016年第6期680-682,共3页Chinese Heart Journal

基　　金：陕西省自然科学基础计划项目资助(2013JM4041)

摘　　要：目的探讨心脏再同步化治疗(CRT)患者双室同步起搏与左心室内同步化的相关性。方法行CRT患者128例,按术后心电图特点分为双室同步起搏组(78例)和双室非同步起搏组(50例)。随访1年,多普勒超声心动图观察测定Ts-SD、Te-SD在不同组中的变化差异,评价左心室内同步化的变化。结果 1双室同步起搏组植入前较植入后Ts-SD〔(45±9)ms vs.(33±7)ms,P<0.05〕、Te-SD〔(41±8)ms vs.(31±8)ms,P<0.05〕有统计学意义;2单因素方差分析示Ts-SD、Te-SD、LVESV比较有统计学意义(P<0.05);3多因素分析示双室同步起搏与Ts-SD(B=-0.052,P=0.000)、Te-SD(B=-0.032,P=0.032)呈线性相关;4双室同步化起搏与Ts-SD行Pearson分析具有相关性(r=-0.933,P=0.000),Ts-SD呈负相关。结论经CRT治疗双室同步起搏组较双室非同步起搏组术后随访过程中左心室内协调性得到改善更加显著。AIM To appraise the correlation between double ventricular synchronous pacing and left ventricular systolic synchronicity after cardiac resynchronization therapy （CRT） in patients for 12 months. METHODS There were 128 patients who underwent CRT from January 2012 to July 2014. Seventy eight patients with double ventricular synchronous pacing and 50 patients not satisfied by ECG were enrolled. The differences of Ts-SD and Te-SD in tissue velocity imaging were studied. RESULTS Ts-SD [ （45 ＋9） ms vs. （33 ＋7） ms, P 〈0. 05] and Te-SD [ （41 ＋8） ms vs. （31 ~8） ms, P 〈0. 05] improved over baseline in 78 patients with double ventricular synchronous pacing. ANOVA showed Ts-S, Te-SD, and LVESV were different （ P 〈 0. 05 ）. Multiple linear regression indicated double ventricular synchronous 0. 032, and with Ts-SD, pacing was aligned with Ts-SD （ B = - 0. 052, P = 0. 000）, Te-SD （ B = - 0. 032, P = Pearson analysis showed negative correlation between double ventricular synchronous pacing r = - 0. 933, P = 0. 000）. CONCLUSION CRT with double ventricular synchronous pacing maybe effective in improving left ventricular systolic synchronicity.

关 键 词：心脏再同步化治疗 心电图 左心室同步化 

分 类 号：R541.6[医药卫生—心血管疾病]