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作 者:车楠[1,2] 张维璐[1] 高军宪 王朝侠 席斐 王安辉[1] 龙泳[1]
机构地区:[1]第四军医大学军队流行病学教研室,陕西西安710032 [2]西安市第九医院神经内科,陕西西安710054 [3]解放军518医院检验科,陕西西安710043
出 处:《心脏杂志》2016年第6期686-689,共4页Chinese Heart Journal
基 金:陕西省自然科学基金项目资助(2014JM2-8143);陕西省留学人员科技活动项目资助(2014JM2-8143,Y)
摘 要:目的探讨西安地区H型高血压等相关因素与脑卒中的关系,为预防与控制措施提供理论依据。方法本研究采用病例对照的研究设计,连续收集西安市第九医院神经内科住院患者400例为研究对象,其中脑卒中患者作为病例组,非脑卒中患者作为对照组,对其一般人口学特征、家族史、吸烟史、饮酒史、高血压、H型高血压、既往病史、性格类型等与脑卒中之间的关系进行研究。数据通过SPSS18.0处理,主要采用单因素和调整因素的Logistic回归模型进行统计分析。结果单因素分析显示,高龄、男性、文化程度低、脑力劳动、吸烟、高血压、H型高血压、亲属脑卒中史、亲属心脏病史以及内向型性格等因素与西安地区脑卒中具有相关性,其中一级亲属的脑卒中和心脏病史的危险性均高于普通亲属;调整年龄性别的Logistic回归分析显示,高血压、H型高血压、一级亲属脑卒中史和心脏病史等因素与西安地区脑卒中具有相关性;在轻度脑卒中和中重度脑卒中的比较中,文化程度低、内向型性格、吸烟和高血压与中重度脑卒中具有相关性。结论高血压、H型高血压、一级亲属脑卒中史和心脏病史等因素与西安地区脑卒中的发生关系密切,高血压、文化程度低、内向型性格和吸烟与中重度脑卒中的发生相关。AIM To study the relationship between H-type hypertension and stroke in Xi'an area METHODS A case-control study was designed and 400 consecutive inpatients in the Department of Neurology, Ninth Hospital of Xi 'an were enrolled. Patients were divided into two groups (case and control) according to stroke diagnosis. Data were analyzed and compared between groups including age, gender, educational level, body mass index ( BMI), marital status, occupation, cigarette smoking, alcohol, diabetes mellitus, hypertension, H-type hypertension, family history of stroke, family history of heart disease, and social characteristics. RESULTS Stroke was negatively correlated with older age, male gender, low educational level, intellectual occupation, cigarette smoking, hypertension, H-type hyper- tension, family history of stroke, and family history of heart diseases. OR values of family history of stroke and heart diseases in parents were higher than those of other relatives. Hypertension, low educational level, introversion, and cigarette smoking were correlated with moderate/severe stroke. CONCLUSION Hypertension, H-type hypertension, parental history of stroke, and parental history of heart diseases are risk factors for stroke. Low factors for moderate/severe educational level, introversion, cigarette smoking, and hypertension are risk stroke in the Xi'an area.
分 类 号:R544.1[医药卫生—心血管疾病]
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