上海市成人人体测量学指标与糖脂代谢紊乱的相关性  

Correlation of anthropometric indices with risk factors for diabetes and dyslipidemia in an adult population in Shanghai

作　　者：陈光榆[1] 李锐[2] 李新建[2] 朱蝉艳 孙婉璐[1] 范建高[1] 

机构地区：[1]上海交通大学医学院附属新华医院消化内科脂肪肝诊治中心,200092 [2]上海市疾病预防控制中心慢病科

出　　处：《中华糖尿病杂志》2016年第11期672-676,共5页CHINESE JOURNAL OF DIABETES MELLITUS

基　　金：国家重点基础研究发展计划（2012CB517501）;国家自然科学基金（81070322、81270491）;上海市科委重点项目（09140903500、10411956300）;上海市卫生系统优秀学科带头人计划（XBR2011007）

摘　　要：目的探讨和比较人体学测量学指标与上海地区成人糖脂代谢紊乱的关系。方法利用2002年10月至2003年9月上海地区糖尿病流行病学调查中14336名成人的完整资料，分析体质指数、腰围、腰臀比和腰高比4项指标与血糖和血脂的相关关系，并比较该4项指标的糖尿病和高脂血症受试者工作特征（ROC）曲线及其最佳切点。以多因素Logistic逐步回归分析4项指标对糖尿病和高脂血症的预测价值。结果体质指数、腰围、腰臀比和腰高比均与血糖和血脂指标密切相关（偏相关系数0．034—0．261，均P〈0．01），且不受性别和年龄影响；腰高比筛检糖尿病和高脂血症的最佳切点分别为0．51和0．49，ROC曲线分析显示腰高比的曲线下面积为最大（分别0．712和0．642）；经多因素调整后，以腰高比≥0．5评估糖尿病、高甘油三酯血症和高胆固醇血症的OR值（1．67、2．04和1．53）为最大。结论人体测量学指标与上海地区成人糖脂代谢紊乱关系密切，其中以腰高比的预测价值为最佳，可作为筛查代谢紊乱的首要指标。Objective To evaluate the correlation between anthropometric indices and diabetes and dyslipidemia in Chinese adults. Methods A total of 14 336 participants with complete data from Shanghai Adults Diabetes Epidemiology Study during 2002 to 2003 were recruited. The con＇elatiou between body mass index（BMI）, waist circumference, waist-hip ratio （WHR） and waist-height ratio （WHtR） and blood glucose and lipids were analyzed; receiver operating characteristic （ROC） curve analysis and the best cut-off point of the four indicators for diabetes and hyperlipidemia were compared; multi-variable logistic regression analysis was also conducted. Results All anthropometric （BMI, waist circumference, WHR and WHtR） indices were closely correlated with blood glucose and lipid levels（partial correlation coefficient 0.034-0.261, P〈0.01）, which were not affected by gender and age. Compared with other anthropometric indicators, WHtR was found to have the largest area under the ROC curve （0.712 for diabetes and 0.642 for hyperlipidemia）, and the best cut-off points of diabetes and hyperlipidemia were 0.51 and 0.49, respectively. Multi-variable logistic regression analysis showed WHtR had the highest degree of association with diabetes, hypertriglyceridemia and hypercholesterolemia （OR=1.67, 2.0 and 1.53）. Conclusion There is a close relationship between anthropometric indices and diabetes and lipid metabolic disorder in adult population of Shanghai. WHtR can serve as an important indicator of screening assessment.

关 键 词：糖尿病 脂代谢障碍 人体测量术 腰围身高比值 

分 类 号：R587.1[医药卫生—内分泌]