超声声速匹配联合磁共振弥散成像技术在老年慢性乙肝纤维化中的应用价值  

Analysis on the application value of ultrasonic velocity matching combined with MR diffusion-weighted imaging in elderly patients with chronic hepatitis B fibrosis

作　　者：赖小伟[1] 陈方红[1] 黄岩花[1] 周宁[1] 

机构地区：[1]浙江省丽水市中心医院超声科,浙江丽水323000

出　　处：《中国现代医生》2016年第30期100-102,106,共4页China Modern Doctor

基　　金：浙江省医药卫生一般研究计划项目(2015KYB453)

摘　　要：目的观察超声声速匹配联合磁共振弥散成像技术在老年慢性乙肝纤维化中的评价效果及价值。方法选取老年慢性乙型病毒性肝炎患者102例,设为观察组。其中纤维化患者74例,28例无纤维化。取同期入院健康体检者102例,设为对照组。两组均采用超声声速匹配技术测量不同肝部位区域速度指数,采用磁共振弥散成像技术测定弥散系数(ADC)值。结果观察组患者中随着肝硬化分期的不断加重,不同弥散敏感系数下弥散系数值均出现下降,且弥散敏感系数越大,弥散系数值越小;观察组肝左叶及肝右叶被膜下区域速度指数显著高于对照组;观察组患者分级越高,肝左叶及肝右叶被膜下区域速度指数越高,不同分级之间比较,差异有统计学意义(P<0.05)。结论超声声速匹配联合磁共振弥散成像技术在不同分期老年慢性乙肝纤维化中效果理想,值得推广应用。Objective To observe the evaluation effects and value of ultrasonic velocity matching combined with magnetic resonance diffusion-weighted imaging in elderly patients with chronic hepatitis B fibrosis. Methods 102 elderly patients with chronic hepatitis B were selected in the study, who were assigned to the observation group, among which 74 patients with fibrosis and 28 patients without fibrosis. A total of 102 healthy subjects were selected in this study, who were assigned to the control group. The velocity indices of different liver regions were measured by ultrasonic velocity matching technique, and diffusion coefficient（ADC） values were measured by magnetic resonance diffusion imaging technique. Results In the observation group, the diffusion coefficient was decreased with the increasing stage of hver cirrhosis, and the larger the diffusion sensitivity coefficient was, the smaller the diffusion coefficient was; the velocity index of left lower lobe and lower right lobe in the observation group was significantly higher than that in the control group; the higher the grade of the patients was in the observation group, the higher the velocity index of the left lower lobe and the right lobe of the liver was in the subfascial region, and the differences in different grades were statistically significant（P〈0.05）. Conclusion Ultrasonic velocity matching combined with MR diffusion-weighted imaging is effective in different stages of chronic hepatitis B fibrosis in elderly patients, which is worthy of popularization and application.

关 键 词：超声声速匹配 磁共振弥散成像技术 慢性乙肝纤维化 弥散系数 

分 类 号：R318.04[医药卫生—生物医学工程]