极端微生物及其功能和应用研究进展  

Research Advances on the Functions and Applications of Extremophile

作　　者：庄原[1] 彭程[1] 叶波平[1] 

机构地区：[1]中国药科大学生命科学与技术学院,江苏南京210009

出　　处：《药物生物技术》2016年第5期442-446,共5页Pharmaceutical Biotechnology

摘　　要：极端微生物由于生长环境特殊,因而具有较为特殊的遗传背景和代谢途径,可产生结构新颖的活性代谢物质和一些特殊功能的酶类,在药物的研发和工农业生产中具有良好的应用前景。该文对近年来有关极端微生物在药物先导化合物的发现、农业生产中的生物防治以及环境治理方面的应用进行了总结。Because of the special environment of growth,extremophiles are thought to have a more specific genetic background and unique metabolic pathways to adapt its living conditions.Therefore,extremophiles are supposed to have the ability to produce some novel active metabolism for drug screening,or even to secrete special enzymes which can be used in enzymatic engineering,biological control and environmental pollution treatment.The extensive literature linking extremophile to industrial and agricultural application and environmental pollution treatment have been reviewed in recent years.

关 键 词：极端微生物 分类 酶 功能 应用 

分 类 号：Q93[生物学—微生物学]