固相萃取-超高效液相色谱/串联质谱法同时测定水中27种磺酰脲类除草剂  

Simultaneous Determination of Sulfonylureas Herbicides in Water Using Solid Phase Extraction-Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry

作　　者：吴春英[1,2] 白鹭[1] 谷风[1] 陆文龙[1] 

机构地区：[1]吉林化工学院资源与环境工程学院,吉林吉林132022 [2]清华大学环境学院环境模拟与污染控制国家重点联合实验室,北京100084

出　　处：《分析科学学报》2016年第6期783-788,共6页Journal of Analytical Science

基　　金：中国博士后科学基金(No.20080440374)

摘　　要：采用固相萃取,用超高效液相色谱-串联质谱法（UPLC-MS/MS）建立了水中27种磺酰脲类除草剂的分析方法。通过对固相萃取柱、淋洗液、流动相等的优化,确定以Oasis HLB固相萃取柱、乙腈为淋洗液、0.1%乙酸-甲醇（7∶3,V/V）为流动相做水样预处理。在最优条件下,目标物回收率均为79.8%~124.5%,相对标准偏差（RSDs）为6.9%~9.6%,线性范围均为1~2 000μg/L,线性相关系数（R2）在0.999以上。该方法具有检测限低、回收率高等优点,经实际样品测试,可适用于水中27种磺酰脲类除草剂残留的同时检测。An analytical method for simultaneous determination of 27 sulfonylireas herbicides in water samples was developed by solid phase extraction-ultra high performance liquid chromatography-tandem mass spectrometer（UPLC-MS/MS）. An Oasis HLB solid phase extraction column with acetonitrile as washing solution and 0.1% acetic acid-methanol（7：3,V/V） as the UPLC mobile phases were selected for sample pretreatment and chromatographic separation, separately. Under the optimized conditions,the target recoveries ranged from 79.8% to 124.5% in water with the relative standard deviations（RSDs） from 6.9% to 9.6%. The linear range was 1-2 000μg/L with correlation coefficients（R2） no less than 0. 999. The method can be applied to simultaneous determination of 27 sulfonylureas herbicides in environmental water samples because of its low detection limits and high recoveries.

关 键 词：固相萃取 超高效液相色谱-串联质谱法 磺酰脲类除草剂 回收率 

分 类 号：O657.63[理学—分析化学]