气相色谱法检测黄芪饮片中有机氯农药残留量  

Determination of organochorine pesticide residues in Radix Astragali by GC-ECD

作　　者：杜妍[1,2] 宗凯 夏泉[3] 余晓峰 

机构地区：[1]安徽出入境检疫检验局,安徽合肥230022 [2]安徽医科大学药学院,安徽合肥230032 [3]安徽医科大学第一附属医院,安徽合肥230022

出　　处：《安徽医药》2016年第10期1857-1861,共5页Anhui Medical and Pharmaceutical Journal

基　　金：国家质检总局科技计划项目(2015IK001)

摘　　要：目的了解目前安徽省部分医疗机构中所使用的的黄芪中药饮片有机氯农药残留量的现状。方法从安徽省部分三级甲等医疗机构采集样品并收集相关产地信息,按照2010版《中国药典》中有机氯农药残留气相色谱检测方法,黄芪饮片粉粹后以有机溶剂超声提取、用浓硫酸磺化后,采用不分流进样方式,经两次程序升温技术分离,后采用电子捕获检测器(ECD)检测,外标法计算含量。结果所采集的黄芪饮片中有机氯农药残留远低于《中国药典》2010年版一部规定要求。但不同产地来源的样品仍存在差异。结论该方法可以快速准确的检测黄芪饮片中有机氯农药残留的含量,为安全用药提供保障。Objective To investigate organochlorine pesticides residue in Radix Astragali collected from different medical institutions.Methods We collected samples and information of sources from different medical institutions. According to the ＂ Chinese pharmacopoeia＂ we used gas chromatography method. Samples were extracted with mixed solvents by ultrasonic,then purified with sulfuric acid.Splitless injection was adopted before the detection of ECD detector and determination of contents by external standard method. Results Organochlorine pesticides residue in Radix Astragali produced in Gansu and Inner Mongolia were much lower than the standard of Chinese pharmacopeia,but there were some differences among samples from different sources. Conclusions This method is quick and accurate,which can provide a guarantee for the safe use of drug.

关 键 词：黄芪饮片 有机氯农药残留 现状调查 

分 类 号：R284.1[医药卫生—中药学] O657.71[医药卫生—中医学]