利多卡因咽喉表面麻醉对手术患者血流动力学的影响  

Influence of lidocaine throat surface anesthesia on hemodynamics in patients with surgery

作　　者：赖烯束 卢彬[1] 冯会和[2] 

机构地区：[1]自贡市第四人民医院麻醉科,四川自贡643000 [2]自贡市第四人民医院普外科,四川自贡643000

出　　处：《中国生化药物杂志》2016年第11期121-123,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探讨利多卡因咽喉表面麻醉对手术患者血流动力学的影响。方法选取2013年1月至2016年4月在我院普外科行上腹部手术治疗的患者118例,随机分为观察组(n=68)和对照组(n=50),观察组给予利多卡因咽喉表面麻醉,对照组不给予咽喉表面麻醉,观察2组麻醉诱导前(T0)、气管插管前(T1)及插管后1min(T2)、5min(T3)和10min(T4)、心率(heart rate,HR)、收缩压(systolic blood pressure,SBP)、舒张压(diastolic blood pressure,DBP)和平均动脉压(mean arterial pressure,MAP)等指标。结果观察组T1、T2时SBP、DBP和MAP明显低于对照组(P<0.05);观察组T4时SBP低于对照组(P<0.05);观察组和对照组各时期HR比较无统计学意义;观察组呛咳发生率及呛咳分级分别为22.06%和(1.20±0.73),明显低于对照组58.00%和(3.18±0.57)(P<0.05);观察组和对照组呼吸恢复时间和睁眼时间比较差异无统计学意义。结论利多卡因咽喉表面麻醉可适当降低手术患者气管插管时的心血管反应以及术后呛咳。Objective To investigate the effects of lidocaine throat surface anesthesia on hemodynamics in patients with surgical operation.Methods From January 2013 to April 2016,118 cases of patients with upper abdominal surgery in our hospital,were randomly divided into observation group（ n = 68） and control group（ n = 50）,the observation group were given lidocaine throat surface anesthesia,the control group did not give the throat surface anesthesia,observed two groups before induction of anesthesia（ T0）,before intubation（ T1） and after 1 min（ T2）,5min（ T3） and10min（ T4） intubation,heart rate（ HR）,systolic blood pressure（ SBP）,diastolic blood pressure（ DBP） and mean arterial pressure（ MAP） and other indicators. Results The observation group T1 and T2 SBP,DBP,MAP were significantly lower than control group（ P〈0. 05）; observation group SBP at T4 was lower than control group（ P〈0. 05）; HR of observation group and control group was not statistically significant at each period; The incidence of cough and cough classification in observation group were 22. 06% and（ 1. 20 ± 0. 73）,which were significantly lower than that of control group 58. 00%and（ 3. 18 ± 0. 57）（ P〈0. 05）. The observation group and the control group breathing recovery time and the time of opening eyes difference had no statistically significant. Conclusion The surface of lidocaine anesthesia can reduce the cardiovascular response to tracheal intubation in patients with surgery and postoperative cough.

关 键 词：利多卡因 咽喉表面麻醉 血流动力学 呛咳 

分 类 号：R762[医药卫生—耳鼻咽喉科]