对采用奥曲肽对患有急性水肿型胰腺炎疾病的患者实施治疗的效果观察  

To Use the Octreotide in Patients with Acute Edema Type Pancreatitis Dis-ease Treatment Effect is Observed

作　　者：陈凝[1] 林棱[1] 

机构地区：[1]福建医科大学省立临床医学院综合内科,福建福州350001

出　　处：《中外医疗》2016年第33期121-123,共3页China & Foreign Medical Treatment

摘　　要：目的针对奥曲肽对急性水肿型胰腺炎患者的治疗效果进行评估。方法随机抽选2014年1月—2016年2月在该院接受救治的急性水肿型胰腺炎患者140例为研究对象,结合患者入院时间先后分为两组。对照组(70例)患者均给予生长抑素酶抑制剂等常规西医治疗,观察组(70例)患者则在此基础上添加奥曲肽治疗,评估两组患者治疗效果差异,同时统计患者腹痛消失时间、血象恢复时间、正常进食时间等指标,测定患者治疗后体内血淀粉酶水平以及血清C反应蛋白含量,统计患者不良反应发生率。结果观察组患者治疗有效率(94.3%)明显高于对照组(80.0%),差异有统计学意义(P<0.05)。观察组患者治疗后腹痛消失时间、血象恢复时间、恢复正常进食时间等均低于对照组,差异有统计学意义(P<0.05)。同时观察组患者治疗后血淀粉酶水平以及血清C反应蛋白含量明显低于对照组,差异有统计学意义(P<0.05)。观察组患者不良反应发生率(7.1%)低于对照组(21.4%),差异有统计学意义(P<0.05)。结论常规西医基础上添加奥曲肽治疗急性水肿型胰腺炎患者效果显著,能促使患者症状更快缓解且优化患者身体指标,同时安全性高,值得临床推广。Objective In view of the octreotide in patients with acute edema type pancreatitis to evaluate therapeutic effect.Methods Random selected in January 2014 — February 2016 in our hospital treated 140 cases of patients with acute edema type pancreatitis as the research object, combined with patients hospitalized time has been divided into two groups.Control group（70 cases） patients were given somatostatin enzyme inhibitors such as conventional western medicine treatment,the observation group（70 cases） patients, on the basis of adding the peptide treatment, evaluation of two groups of patients with different treatment effects, and statistical recovery time of patients with abdominal pain disappear time, blood picture,normal eating time indicators, such as determination of blood amylase levels after treatment and the content of serum c-reactive protein, statistical patients incidence of adverse reactions. Results The observation group of patients treatment efficient（94.3%） is significantly higher than control group（80.0%）, there is statistical significance difference（P 〈0.05）. Observation group after treatment in patients with abdominal pain disappear time, recovery time, back to normal eating urinalysis performed time are lower than the control group, significant difference（P 〈0.05）. At the same time observation group of patients after treatment of blood amylase levels and serum c-reactive protein levels significantly lower than the control group,significant difference（P 〈0.05）. Observation group of patients incidence of adverse reactions（7.1%） is lower than the control group（21.4%） and significant difference（P 〈0.05）. Conclusion On the basis of conventional western medicine to add the effect of octreotide in treatment of acute edema type pancreatitis patients, can cause symptoms resolve faster and optimization patients body index, at the same time, high safety, worth clinical promotion.

关 键 词：奥曲肽 急性水肿型胰腺炎 症状缓解 生化指标 不良反应 

分 类 号：R5[医药卫生—内科学]