加味理冲汤治疗非酒精性脂肪肝临床研究  

Clinical Study on the Treatment of Non Alcoholic Fatty Liver by Modified Decoction for Treating Non Alcoholic Fatty Liver Disease

作　　者：张玉峰[1] 叶坤英[1] 韩佳瑞[1] 

机构地区：[1]河南中医药大学,河南郑州450046

出　　处：《中外医疗》2016年第33期176-179,共4页China & Foreign Medical Treatment

基　　金：河南省中医药科学研究专项课题(2013ZY02057)

摘　　要：目的研究证实加味理冲汤治疗非酒精性脂肪肝的临床疗效。方法采用随机对照的试验方法 ,整群纳入2014年3月—2016年3月该院收治的102例非酒精性脂肪肝患者,其中治疗组51例,对照组51例,在两组接受基础治疗的前提下,对照组在一般治疗基础上加用水飞蓟宾胶囊,2粒/次,3次/d,饭后服用。治疗组同时加用加味理冲汤,1剂/d,疗程8周。比较两组治疗前后临床症状、体征、血脂指标及影像改变情况。结果 2组治疗后肝功能指标ALT、AST、rGT均较治疗前显著改善(P<0.05),且治疗组改善效果优于对照组(P<0.05),治疗组总有效率80.4%,高于对照组56.9%,对比差异具有统计学意义(P<0.05)。结论加味理冲汤治疗非酒精性脂肪肝能够降低血脂,改善肝功能,减轻肝脏脂肪病变。Objective To prove that the modified Li Chong Decoction in the treatment of non alcoholic fatty liver; clinical.Methods Group selection a randomized controlled trial were included in March 2014 to March 2016 in our hospital 102 cases of non-alcoholic fatty liver disease, the treatment group 51 cases, 51 cases in the control group, the treatment groups receiving basic premise under the control group received general treatment based on water silibinin capsule, a two, three times a day after meals. The treatment group added in processing punch flavored soup, one dose per day, for 8 weeks. Clinical symptoms, signs, serum lipids and imaging changes before and after treatment were compared. Results After treatment,liver function ALT, AST, r-GT than those before treatment significantly improved（P 〈0.05）, and the effect of improving the treatment group than the control group（P 〈0.05）. Treatment group, the total efficiency of 80.4%, higher than 56.9%, compared to a statistically significant difference（P〈 0.05）. Conclusion Modified Lichong Decoction in the treatment of non alcoholic fatty liver disease can reduce blood fat, improve liver function, reduce fatty liver disease.

关 键 词：非酒精性脂肪肝 中医药 肝功能 

分 类 号：R5[医药卫生—内科学]