侧链含芳基亚甲胺基均三唑硫酮的合成、晶体结构及生物活性研究  

Synthesis,crystal structure and biological activity study on arylidene amino 1,2,4-triazole thiones

作　　者：周三女 吴先辉 田妍基 刘丽清 

机构地区：[1]宁德职业技术学院,福建福安35000

出　　处：《化学研究与应用》2016年第12期1718-1725,共8页Chemical Research and Application

基　　金：福建省中青年教育科研项目(JAT160907)资助

摘　　要：用2H-4-氨基-5-邻乙氧基苯基-1,2,4-三唑-3(4H)-硫酮与芳醛反应,合成了一系列2H-4-芳基亚甲胺基-5-邻乙氧基苯基-1,2,4-三唑-3(4H)-硫酮类Schiff碱。用元素分析、IR、NMR、MS、X-射线晶体衍射等分析技术对结构进行了确认与表征,并对部分产物进行了初步的植物生长调节活性测试。测定表明,目标化合物对双子叶植物(萝卜)和单子叶植物(小麦)的生长均有显著的抑制作用。By the reaction of 2H-4-amino-5-（ 2-ethoxyphenyl）-1,2,4-triazole-3（ 4H）-thione and aromatic aldehydes,a series of new Schiff bases of 2H-4-arylidene amino-5-（ 2-ethoxyphenyl）-1,2,4-triazole-3（ 4H）-thiones were synthesized. In addition,their structures were charaterized by elemental analysis,IR,NMR,MS,X-ray diffraction analysis.The plant growth regulating effects of all the compounds were evaluated. The results showed that these target compounds had remarkable inhibitory activities on the dicotyledon（ radish） and the monocotyledon（ wheat）.

关 键 词：2H-4-芳基亚甲胺基-5-邻乙氧基苯基-1 2 4-三唑-3(4H)-硫酮 合成 晶体结构 生物活性 

分 类 号：O626[理学—有机化学]