老年糖尿病患者应用氟喹诺酮类致血糖紊乱的分析  

Analysis of Blood Glucose Disorder Induced by Fluoroquinolones in Elderly Diabetic Patients

作　　者：许双临[1] 黄维英[1] 

机构地区：[1]福建医科大学附属宁德市医院,福建宁德352100

出　　处：《糖尿病新世界》2016年第22期90-91,共2页Diabetes New World Magazine

摘　　要：目的探讨氟喹诺酮类对老年糖尿病患者血糖的影响。方法临床药师通过对3例老年糖尿病患者应用氟喹诺酮类抗感染治疗过程中出现血糖紊乱的不良反应病例进行分析,探讨其可能的机制及危险因素。结果氟喹诺酮类可能引起老年糖尿病患者血糖异常,药师建议氟喹诺酮类不作为此类患者的首选抗感染用药,提高临床用药的安全性。结论老年糖尿病患者应慎用氟喹诺酮类,药师在临床开展药学服务时尤其需关注此类药物的用药安全。Objective To investigate the effect of fluoroquinolones on blood glucose in elderly patients with diabetes mellitus. Methods The clinical pharmacist analyzed the adverse reactions of 3 patients with diabetes mellitus who were treated with fluoroquinolone during the course of anti-infection treatment,and investigate the possible mechanism of action and risk factors. Results Fluoroquinolone may cause pathoglycemia in elderly diabetic patients. Pharmacists suggested that fluoroquinolones should not be used as the first choice for anti-infective drugs in such patients, thus improving the safety of clinical use. Conclusion Fluoroquinolones should be used with caution in elderly patients with diabetes mellitus. Pharmacists should pay more attention to the safety of drug administration in clinical practice.

关 键 词：糖尿病 氟喹诺酮 血糖紊乱 老年 危险因素 

分 类 号：R587.1[医药卫生—内分泌]