CBA技术与两种常用快速检测技术在结核病诊断运用中的比较  

Comparison of CBA technology and other two commonly used rapid detection techniques in the diagnosis of tuberculosis

作　　者：刘君[1] 裴豪[1] 王俊[1] 戴亚萍[1] 翟桦梓 陈玉梅[1] 

机构地区：[1]无锡市第五人民医院,江苏无锡214005

出　　处：《中华医院感染学杂志》2016年第24期5569-5571,共3页Chinese Journal of Nosocomiology

基　　金：江苏省自然科学基金面上研究项目(BK20151113)

摘　　要：目的通过与两种常用的结核病快速诊断技术的比较,评价CBA检测方法在结核病诊断中的价值,为临床治疗提供参考依据。方法选取医院2015年3月-12月收治的住院患者191例,运用CBA技术、T-SPOT和结核分枝杆菌抗体检测对所有入组对象进行双盲检测,并对检测结果统计分析。结果 CBA检测的敏感性为86.82%,比T-SPOT 75.19%和结核分枝杆菌抗体检测38.76%均高,差异有统计学意义(P<0.05);CBA检测结果的特异性为91.94%,比T-SPOT 82.26%和结核分枝杆菌抗体检测的83.87%均高。结论 CBA技术的检测结果能有效的区分活动性结核病和其他肺部疾病,有利于控制结核病疫情的流行,为实现最终消灭结核病的长远目标提供了可靠的技术方法。OBJECTIVE To evaluate the value of CBA technology in the diagnosis of tuberculosis by comparison with two commonly used rapid detection techniques,so as to provide references for clinical treatment.METHODS A total of 191 patients were choosed in hospital from Mar.2015 to Dec.2015.All subjects were double-blind detected by using CBA technology,T-SPOT and TB antibody detection,then the test results were statistically analyzed.RESULTS The sensitivity of CBA was 86.82%,which was higher than 75.19% of T-SPOT and 38.76% of TB antibody detection,and the differences were significance（P〈0.05）.The specificity of CBA was 91.94,which was higher than 82.26% of T-SPOT and 83.87% of TB antibody detection.CONCLUSION The results of CBA technology can effectively distinguish between active TB and other lung diseases,has great significance to control the development of TB epidemic,and provide a reliable technique to achieve the eventual goals of eliminating TB.

关 键 词：肺结核 CBA技术 T-SPOT 结核菌抗体检测 

分 类 号：R521[医药卫生—内科学]