血细胞炎性因子在膀胱癌感染患者中的表达水平研究  

Expression levels of blood inflammatory factors of infected patients with bladder cancer

作　　者：田丰[1] 郭世龙[2] 郭珊[2] 薛伍洋[1] 郭新胜[1] 

机构地区：[1]新乡医学院第二附属医院检验科,河南新乡453002 [2]新乡市中心医院泌尿外科,河南新乡453000

出　　处：《中华医院感染学杂志》2016年第24期5653-5655,共3页Chinese Journal of Nosocomiology

基　　金：河南省科技攻关资助项目(0124170744)

摘　　要：目的研究与观察血细胞炎性因子在膀胱癌感染患者中的表达水平,为本病患者治疗措施的制定提供参考依据。方法选取2014年12月-2016年4月医院收治45例膀胱癌感染患者为A组,同期选取45例膀胱癌无感染患者为B组,45名健康人员为C组,比较3组、A组与B组中不同膀胱癌分期患者的检测水平。结果 A组血清抗炎因子IL-4、IL-10、IL-37及APN水平分别为(2.21±0.25)ng/ml、(30.68±3.27)pg/ml、(50.17±3.34)pg/ml及(4.18±0.52)mg/L,其均差于B组,B组则差于C组,差异均有统计学意义(P<0.05)。结论血细胞炎性因子在膀胱癌感染患者中的表达水平呈现明显异常的状态,且感染对于不同分期膀胱癌患者的上述指标表达均有较大影响,应给予充分重视。OBJECTIVE To study and observe the expression levels of blood inflammatory factors of patients with bladder cancer and infection,in order to provide evidence for the treatment measures of the patients.METHODS A total of 45 patients with bladder cancer and infection from Dec.2014 to Apr.2016 were set as group A,45 patients with bladder cancer and without infection at the same time were set as group B,and 45 healthy persons were set as group C.The serum anti-inflammatory and pro-inflammatory factors levels of the three groups were detected,then the detection levels of the three groups,group A and group B with different stages of bladder cancer were compared.RESULTS The serum pro-inflammatory factors IL-4,IL-10,IL-37 and APN of group A were（2.21±0.25）ng/ml,（30.68±3.27）pg/ml,（50.17±3.34）pg/ml and（4.18±0.52）mg/L,respectively,which were all worse than those of group B,and the levels of group B were all worse than those of group C,and there were significant differences（P〈0.05）.CONCLUSIONThe expression levels of blood inflammatory factors of patients with bladder cancer and infection show obviously abnormal,and the influence of the infection for those indexes of patients with different stages of bladder cancer are great,so they should be paid to more attention.

关 键 词：血细胞炎性因子 膀胱癌 感染 

分 类 号：R446.11[医药卫生—诊断学]