细菌性阴道疾病患者高危型人乳头状瘤病毒感染及局部微循环的变化观察  

Observation on the changes of high-risk human papilloma virus infection situation and local microcirculation of patients with bacterial vaginal disease

作　　者：张莹[1] 孙晖[2] 王英[3] 郭清普[1] 赵会珍[1] 

机构地区：[1]郑州大学附属医院南阳市中心医院消毒供应中心二部,河南南阳473000 [2]郑州大学附属医院南阳市中心医院妇二科,河南南阳473000 [3]郑州大学附属医院南阳市中心医院妇三科,河南南阳473000

出　　处：《中华医院感染学杂志》2016年第24期5680-5682,共3页Chinese Journal of Nosocomiology

基　　金：河南省杰出人才创新基金资助项目(0524157309)

摘　　要：目的观察及研究细菌性阴道疾病患者高危型人乳头状瘤病毒(HPV)感染及局部微循环的变化情况,为本病的诊治提供依据。方法选取2015年6月-2016年7月48例细菌性阴道病患者为观察组,同期选取48名健康妇女为对照组,比较两组妇女高危型HPV感染及局部微循环情况。结果观察组HPV16、HPV18及其他高危型HPV检出率分别为31.25%、37.50%及33.33%,均高于对照组的6.25%、6.25%及4.17%,观察组宫颈局部微循环差于对照组,且观察组轻度、中度与重度疾病患者高危型HPV感染情况及局部微循环也存在明显差异,差异均有统计学意义(P<0.05)。结论细菌性阴道疾病患者高危型HPV感染情况及局部微循环明显异于健康妇女,且不同严重程度患者之间也存在一定差异,应给予充分的重视与干预。OBJECTIVE To observe and study the changes of high-risk human papilloma virus（HPV）infection situation and local microcirculation of patients with bacterial vaginal disease,in order to provide evidence for the diagnose and treatment of the disease.METHODS A total of 48 patients with bacterial vaginal disease from Jun.2015 to Jul.2016 were selected as observation group,48 healthy women were selected as control group,and the highrisk HPV infection situation and local microcirculation of the two groups were compared.RESULTS The detection rates of HPV16,HPV18 and other high-risk HPV of observation group were 31.25%,37.50% and 33.33%,respectively,which were all higher than 6.25%,6.25% and 4.17% of control group,the cervical local microcirculation of observation group were worse than that of control group,and the high-risk HPV infection situation and local microcirculation of observation group with mild,moderate and severe disease had significant differences（P〈0.05）.CONCLUSIONThe high-risk HPV infection situation and local microcirculation of patients with bacterial vaginal disease are obviously different to those of healthy women,and the differences of patients with different severities of disease are obvious,so the indexes should be paid enough attention and intervention.

关 键 词：细菌性阴道疾病 高危型人乳头状瘤病毒感染 局部微循环 

分 类 号：R373[医药卫生—病原生物学]